Influence of digitalis on left ventricular functional response to exercise in congestive heart failure

C. Morisco, A. Cuocolo, M. Romano, A. Nappi, G. Iaccarino, M. Volpe, M. Salvatore, B. Trimarco

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

This was a double-blind, placebo-controlled, crossover study designed to determine the influence of digitalis treatment on left ventricular (LV) response to physical exercise in patients with congestive heart failure (CHF). In 10 patients with CHF (ejection fraction 29 ± 2%), LV function was assessed during upright bicycle exercise using an ambulatory radionuclide detector for continuous noninvasive monitoring of cardiac function. Exercise was performed during control conditions and after a 3-week treatment with digoxin (0.25 mg/day orally) or placebo. Ten normal volunteers matched for sex and age constituted the control group. In normals, exercise ejection fraction and end-diastolic volume increased (both p

Original languageEnglish
Pages (from-to)480-485
Number of pages6
JournalThe American Journal of Cardiology
Volume77
Issue number7
DOIs
Publication statusPublished - 1996

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Digitalis
Heart Failure
Exercise
Placebos
Digoxin
Left Ventricular Function
Radioisotopes
Cross-Over Studies
Healthy Volunteers
Control Groups
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Influence of digitalis on left ventricular functional response to exercise in congestive heart failure. / Morisco, C.; Cuocolo, A.; Romano, M.; Nappi, A.; Iaccarino, G.; Volpe, M.; Salvatore, M.; Trimarco, B.

In: The American Journal of Cardiology, Vol. 77, No. 7, 1996, p. 480-485.

Research output: Contribution to journalArticle

Morisco, C. ; Cuocolo, A. ; Romano, M. ; Nappi, A. ; Iaccarino, G. ; Volpe, M. ; Salvatore, M. ; Trimarco, B. / Influence of digitalis on left ventricular functional response to exercise in congestive heart failure. In: The American Journal of Cardiology. 1996 ; Vol. 77, No. 7. pp. 480-485.
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