TY - JOUR
T1 - Influence of digitalis on left ventricular functional response to exercise in congestive heart failure
AU - Morisco, C.
AU - Cuocolo, A.
AU - Romano, M.
AU - Nappi, A.
AU - Iaccarino, G.
AU - Volpe, M.
AU - Salvatore, M.
AU - Trimarco, B.
PY - 1996
Y1 - 1996
N2 - This was a double-blind, placebo-controlled, crossover study designed to determine the influence of digitalis treatment on left ventricular (LV) response to physical exercise in patients with congestive heart failure (CHF). In 10 patients with CHF (ejection fraction 29 ± 2%), LV function was assessed during upright bicycle exercise using an ambulatory radionuclide detector for continuous noninvasive monitoring of cardiac function. Exercise was performed during control conditions and after a 3-week treatment with digoxin (0.25 mg/day orally) or placebo. Ten normal volunteers matched for sex and age constituted the control group. In normals, exercise ejection fraction and end-diastolic volume increased (both p
AB - This was a double-blind, placebo-controlled, crossover study designed to determine the influence of digitalis treatment on left ventricular (LV) response to physical exercise in patients with congestive heart failure (CHF). In 10 patients with CHF (ejection fraction 29 ± 2%), LV function was assessed during upright bicycle exercise using an ambulatory radionuclide detector for continuous noninvasive monitoring of cardiac function. Exercise was performed during control conditions and after a 3-week treatment with digoxin (0.25 mg/day orally) or placebo. Ten normal volunteers matched for sex and age constituted the control group. In normals, exercise ejection fraction and end-diastolic volume increased (both p
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U2 - 10.1016/S0002-9149(97)89341-1
DO - 10.1016/S0002-9149(97)89341-1
M3 - Article
C2 - 8629588
AN - SCOPUS:0029868799
VL - 77
SP - 480
EP - 485
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 7
ER -