Influence of membrane fluidity on 5'-nucleotidase activity in isolated hepatocyte plasma membrane

C. Pieri, M. Falasca, F. Moroni, R. Recchioni, F. Marcheselli

Research output: Contribution to journalArticlepeer-review

Abstract

The influence of membrane microviscosity on 5'-nucleotidase activity has been investigated on liver plasma membrane preparations from rats during aging and following diet restriction. In addition the microviscosity of membranes from old rats was changed in vitro by the Active Lipids. During aging the membrane microviscosity increased progressively and in parallel the activity of 5'-nucleotidase decreased. Diet restriction was able to slow down the modification of both parameters. The experiment performed with the Active Lipids further supports that membrane microviscosity modulated the enzyme activity.

Original languageEnglish
Pages (from-to)631-638
Number of pages8
JournalBiochemistry International
Volume25
Issue number4
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Biochemistry

Fingerprint Dive into the research topics of 'Influence of membrane fluidity on 5'-nucleotidase activity in isolated hepatocyte plasma membrane'. Together they form a unique fingerprint.

Cite this