Influence of membrane fluidity on 5'-nucleotidase activity in isolated hepatocyte plasma membrane

C. Pieri, M. Falasca, F. Moroni, R. Recchioni, F. Marcheselli

Research output: Contribution to journalArticle

Abstract

The influence of membrane microviscosity on 5'-nucleotidase activity has been investigated on liver plasma membrane preparations from rats during aging and following diet restriction. In addition the microviscosity of membranes from old rats was changed in vitro by the Active Lipids. During aging the membrane microviscosity increased progressively and in parallel the activity of 5'-nucleotidase decreased. Diet restriction was able to slow down the modification of both parameters. The experiment performed with the Active Lipids further supports that membrane microviscosity modulated the enzyme activity.

Original languageEnglish
Pages (from-to)631-638
Number of pages8
JournalBiochemistry International
Volume25
Issue number4
Publication statusPublished - 1991

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5'-Nucleotidase
Membrane Fluidity
Fluidity
Cell membranes
Hepatocytes
Cell Membrane
Membranes
Nutrition
Rats
Aging of materials
Diet
Lipids
Enzyme activity
Liver
Enzymes
Experiments

ASJC Scopus subject areas

  • Biochemistry

Cite this

Influence of membrane fluidity on 5'-nucleotidase activity in isolated hepatocyte plasma membrane. / Pieri, C.; Falasca, M.; Moroni, F.; Recchioni, R.; Marcheselli, F.

In: Biochemistry International, Vol. 25, No. 4, 1991, p. 631-638.

Research output: Contribution to journalArticle

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