Influenza dell'equilibrio metabolico sulla deformabilita' eritrocitaria nel diabete mellito.

Translated title of the contribution: Influence of metabolic equilibrium on erythrocyte deformability in diabetes mellitus

N. Stufano, C. Sabbà, E. Altomare, M. T. Perna, E. Berardi, G. Vendemiale, O. Albano

Research output: Contribution to journalArticle

Abstract

Red blood cell filtration test (Reid's test) was performed in 23 diabetic patients and in 10 normal subjects and it was related to metabolic equilibrium. Results showed an increase of filtration time in diabetics when compared to controls (35.1'' +/- 2.3; M +/- SEM vs 22.2'' +/- 0.7, p less than 0.001) and a significant correlation to cholesterol (178.7 mg% +/- 8.9, r = 0.40, p less than 0.05), triglycerides (131.3 mg% +/- 20.6, r = 0.72, p less than 0.001) and to glycosylated hemoglobin (10.7% +/- 0.5, r = 0.60, p less than 0.01) in diabetic patients. No correlation was observed in control subjects. The values of red blood cells filtration time observed in diabetics suggest that an altered erythrocyte deformability in diabetic patients can play an important role in peripheral hypoxia and therefore in diabetic microangiopathy.

Translated title of the contributionInfluence of metabolic equilibrium on erythrocyte deformability in diabetes mellitus
Original languageItalian
Pages (from-to)1853-1858
Number of pages6
JournalBollettino della Societa Italiana di Biologia Sperimentale
Volume60
Issue number10
Publication statusPublished - Oct 30 1984

ASJC Scopus subject areas

  • Medicine(all)

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    Stufano, N., Sabbà, C., Altomare, E., Perna, M. T., Berardi, E., Vendemiale, G., & Albano, O. (1984). Influenza dell'equilibrio metabolico sulla deformabilita' eritrocitaria nel diabete mellito. Bollettino della Societa Italiana di Biologia Sperimentale, 60(10), 1853-1858.