Influence of ofloxacin and pefloxacin on human lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production

Massimo Fantoni, Enrica Tamburrini, Federico Pallavicini, Andrea Antinori, Properzio Nervo

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Abstract

The influence of two fluoroquinolone derivatives, ofloxacin and pefloxacin, on lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production was assessed. Pharmacological concentrations did not influence the studied functions, while suprapharmacological concentrations decreased immunoglobulin production.

Original languageEnglish
Pages (from-to)193-196
Number of pages4
JournalJournal of Antimicrobial Chemotherapy
Volume22
Issue number2
DOIs
Publication statusPublished - Aug 1988

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ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)
  • Pharmacology
  • Microbiology

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