Influence of PFO Anatomy on Successful Transcatheter Closure

Eustaquio Onorato, Francesco Casilli

Research output: Contribution to journalArticlepeer-review


Patent foramen ovale (PFO) is considered a risk factor for serious clinical syndromes, the most important of which is cryptogenic stroke in the setting of paradoxic embolism. The safety and feasibility of transcatheter PFO closure have been addressed in several studies; this procedure is performed worldwide with excellent results. Variations in the atrial septal configuration and PFO are frequent and have an impact on the technical aspects and success in transcatheter PFO closure. To minimize the rate of complications of percutaneous closure of PFO, patients must be carefully selected on the basis of morphology and location of the interatrial defect.

Original languageEnglish
Pages (from-to)51-84
Number of pages34
JournalInterventional Cardiology Clinics
Issue number1
Publication statusPublished - Jan 2013


  • Atrial septal aneurysm
  • Atrial septal morphology
  • Complications
  • Cryptogenic stroke
  • Outcomes
  • Paradoxic embolism
  • Patent foramen ovale anatomy
  • Transcatheter closure of patent foramen ovale

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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