TY - JOUR
T1 - Influence of polyethylene terephthalate on the release of growth factors by human endothelial cells
AU - Cenni, Elisabetta
AU - Verri, Elisabetta
AU - Granchi, Donatella
AU - Gamberini, Simonetta
AU - Corradini, Alessandra
AU - Di Leo, Alessandro
AU - Montanaro, Lucio
AU - Pizzoferrato, Arturo
PY - 1999
Y1 - 1999
N2 - The influence of polyethylene terephthalate (PET) on the release of platelet derived growth factor AB (PDGF-AB) and basic fibroblast growth factor (bFGF) by in vitro cultured human endothelial cells was assessed by enzyme immunoassay. No significant differences were observed in the production of PDGF-AB with respect to the negative control cultures. A significant increase was observed in the production of bFGF after 48 and 72 h with respect to the negative control cultures. It can be concluded that PET may induce an increase in the production of basic FGF in endothelial cells.
AB - The influence of polyethylene terephthalate (PET) on the release of platelet derived growth factor AB (PDGF-AB) and basic fibroblast growth factor (bFGF) by in vitro cultured human endothelial cells was assessed by enzyme immunoassay. No significant differences were observed in the production of PDGF-AB with respect to the negative control cultures. A significant increase was observed in the production of bFGF after 48 and 72 h with respect to the negative control cultures. It can be concluded that PET may induce an increase in the production of basic FGF in endothelial cells.
KW - Endothelial cell
KW - Fibroblast growth factor
KW - Platelet derived growth factor
KW - Polyethylene terephthalate
UR - http://www.scopus.com/inward/record.url?scp=0032753677&partnerID=8YFLogxK
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M3 - Article
C2 - 10574606
AN - SCOPUS:0032753677
VL - 10
SP - 891
EP - 900
JO - Journal of Biomaterials Science, Polymer Edition
JF - Journal of Biomaterials Science, Polymer Edition
SN - 0920-5063
IS - 9
ER -