Abstract
The influence of polyethylene terephthalate (PET) on the release of platelet derived growth factor AB (PDGF-AB) and basic fibroblast growth factor (bFGF) by in vitro cultured human endothelial cells was assessed by enzyme immunoassay. No significant differences were observed in the production of PDGF-AB with respect to the negative control cultures. A significant increase was observed in the production of bFGF after 48 and 72 h with respect to the negative control cultures. It can be concluded that PET may induce an increase in the production of basic FGF in endothelial cells.
| Original language | English |
|---|---|
| Pages (from-to) | 891-900 |
| Number of pages | 10 |
| Journal | Journal of Biomaterials Science, Polymer Edition |
| Volume | 10 |
| Issue number | 9 |
| Publication status | Published - 1999 |
Keywords
- Endothelial cell
- Fibroblast growth factor
- Platelet derived growth factor
- Polyethylene terephthalate
ASJC Scopus subject areas
- Biophysics
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Cite this
Cenni, E., Verri, E., Granchi, D., Gamberini, S., Corradini, A., Di Leo, A., Montanaro, L., & Pizzoferrato, A. (1999). Influence of polyethylene terephthalate on the release of growth factors by human endothelial cells. Journal of Biomaterials Science, Polymer Edition, 10(9), 891-900.