Influence of preoperative biliary drainage on surgical outcome after pancreaticoduodenectomy: Single centre experience

F. Francesco Di Mola, Francesca Tavano, R. Rita Rago, Antonio De Bonis, M. Rosa Valvano, Angelo Andriulli, Pierluigi Di Sebastiano

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Controversy prevails on the impact of preoperative biliary drainage (PBD) on postoperative complications and clinical outcome of pancreatic cancer. We determined whether PBD is associated with increased morbidity and mortality rates after pancreaticoduodenectomy. Methods: A total of 131 consecutive patients who underwent pancreaticoduodenectomy (93 jaundiced, 38 with no jaundice) were included in this study. Overall, 57 % of jaundiced patients underwent PBD, while 43 % were not drained. The impact of PBD on postoperative morbidity and mortality was evaluated by means of logistic regression analysis. The Kaplan-Meier method was applied to determine the effect of PBD on survival of patients with malignant lesions. Results: Mortality and morbidity rate was 3 % and 54.6 %, respectively. PBD was demonstrated to be the unique predictor of complications (odds ration [OR]=10.18; 95 % confidence interval [CI], 3.65-28.39, p

Original languageEnglish
Pages (from-to)649-657
Number of pages9
JournalLangenbeck's Archives of Surgery
Volume399
Issue number5
DOIs
Publication statusPublished - 2014

Keywords

  • Jaundice
  • Pancreatic cancer
  • Postoperative complication
  • Preoperative biliary drainage

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

Fingerprint Dive into the research topics of 'Influence of preoperative biliary drainage on surgical outcome after pancreaticoduodenectomy: Single centre experience'. Together they form a unique fingerprint.

Cite this