Influence of pupil size and cataract on retinal nerve fiber layer thickness measurements by stratus OCT

Giacomo Savini, Maurizio Zanini, Piero Barboni

Research output: Contribution to journalArticle

Abstract

AIM: To investigate whether retinal nerve fiber layer (RNFL) thickness, as measured by optical coherence tomography (OCT), is influenced by pupil size and cataract. METHODS: RNFL thickness was measured by means of Stratus OCT (RNFL Thickness 3.4 acquisition protocol) in a group of consecutive patients undergoing phacoemulsification and intraocular lens implantation. Measurements were taken preoperatively without pupil dilation (PR1), preoperatively with pupil dilation (PR2), and 1 month postoperatively without pupil dilation. RESULTS: Twenty-five eyes of 25 patients were enrolled in the study and underwent statistical analysis. Pupil dilation caused RNFL thickness measurements to increase slightly in PR2 compared with PR1; the difference showed to be statistically significant in the 360-degree average measurement (P=0.0456) and in the nasal quadrant (P=0.032), but not in the remaining quadrants. Postoperative measurements were higher than those of PR1 in all quadrants (temporal P=0.011; superior P=0.0098; nasal P

Original languageEnglish
Pages (from-to)336-340
Number of pages5
JournalJournal of Glaucoma
Volume15
Issue number4
DOIs
Publication statusPublished - Aug 2006

Keywords

  • Cataract
  • Optic nerve
  • Optical coherence tomography
  • Pupil

ASJC Scopus subject areas

  • Ophthalmology

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