Influence of saline depletion on the pressure response to acute alpha and beta blockade in hypertensive patients

E. Marchesi, R. Fogary

Research output: Contribution to journalArticle

Abstract

The authors studied the effects of sodium deprivation plus diuretic therapy on the blood pressure response to infusion of an α-β blocking agent in ten essential hypertensive subjects. The results show that the state of sodium balance can modify this response. The blood pressure decrease is in fact significantly greater during sodium depletion. The data suggest an interrelationship between sympathetic activity and sodium balance in hypertensive subjects.

Original languageEnglish
Pages (from-to)313-315
Number of pages3
JournalDrugs under Experimental and Clinical Research
Volume9
Issue number4
Publication statusPublished - 1983

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Sodium
Pressure
Blood Pressure
Diuretics
Therapeutics

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology (medical)
  • Drug Discovery
  • Pharmacology

Cite this

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abstract = "The authors studied the effects of sodium deprivation plus diuretic therapy on the blood pressure response to infusion of an α-β blocking agent in ten essential hypertensive subjects. The results show that the state of sodium balance can modify this response. The blood pressure decrease is in fact significantly greater during sodium depletion. The data suggest an interrelationship between sympathetic activity and sodium balance in hypertensive subjects.",
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