The authors studied the effects of sodium deprivation plus diuretic therapy on the blood pressure response to infusion of an α-β blocking agent in ten essential hypertensive subjects. The results show that the state of sodium balance can modify this response. The blood pressure decrease is in fact significantly greater during sodium depletion. The data suggest an interrelationship between sympathetic activity and sodium balance in hypertensive subjects.
|Number of pages||3|
|Journal||Drugs under Experimental and Clinical Research|
|Publication status||Published - 1983|
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology (medical)
- Drug Discovery