Abstract
The DNA damage induced by mono-, di-, and trinitrochlorobenzenes has been evaluated in brain of male Swiss CD1 mice. The effect seems to be related to the increased content of nitro groups substituents on the chlorobenzene molecule. This class of compounds shows a high degree of specificity for the nervous tissue if compared to well-known carcinogens as NMU and NDMA.
| Original language | Italian |
|---|---|
| Pages (from-to) | 1680-1686 |
| Number of pages | 7 |
| Journal | Bollettino della Societa Italiana di Biologia Sperimentale |
| Volume | 56 |
| Issue number | 16 |
| Publication status | Published - Aug 30 1980 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Funzione della struttura e delle proprieta' chimico-fisiche degli agenti chimici nell'induzione di alterazioni sul dna : nitroclorobenzeni. / Cesarone, C. F.; Bolognesi, C.; Santi, L.
In: Bollettino della Societa Italiana di Biologia Sperimentale, Vol. 56, No. 16, 30.08.1980, p. 1680-1686.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Funzione della struttura e delle proprieta' chimico-fisiche degli agenti chimici nell'induzione di alterazioni sul dna
T2 - nitroclorobenzeni.
AU - Cesarone, C. F.
AU - Bolognesi, C.
AU - Santi, L.
PY - 1980/8/30
Y1 - 1980/8/30
N2 - The DNA damage induced by mono-, di-, and trinitrochlorobenzenes has been evaluated in brain of male Swiss CD1 mice. The effect seems to be related to the increased content of nitro groups substituents on the chlorobenzene molecule. This class of compounds shows a high degree of specificity for the nervous tissue if compared to well-known carcinogens as NMU and NDMA.
AB - The DNA damage induced by mono-, di-, and trinitrochlorobenzenes has been evaluated in brain of male Swiss CD1 mice. The effect seems to be related to the increased content of nitro groups substituents on the chlorobenzene molecule. This class of compounds shows a high degree of specificity for the nervous tissue if compared to well-known carcinogens as NMU and NDMA.
UR - http://www.scopus.com/inward/record.url?scp=0019336034&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019336034&partnerID=8YFLogxK
M3 - Articolo
C2 - 7459089
AN - SCOPUS:0019336034
VL - 56
SP - 1680
EP - 1686
JO - Bollettino della Societa Italiana di Biologia Sperimentale
JF - Bollettino della Societa Italiana di Biologia Sperimentale
SN - 0037-8771
IS - 16
ER -