Influences of locus ceruleus, raphe dorsalis, and periaqueductal gray matter on somatosensory-recipient thalamic nuclei

Marco Schieppati, Ivana Gritti

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Spontaneous and evoked discharge of neurons in the nucleus ventralis posterolateralis (VPL) and spontaneous discharge of neurons in the posterior group and nucleus lateralis posterior (LP) were conditioned by brief trains of stimuli to the locus ceruleus (LC), raphe dorsalis (RD), and periaqueductal gray matter (PAG) in cats anesthetized with pentobarbital or ketamine. Stimulation of LC and RD was without effect on VPL neurons, but induced a long-latency, long-lasting inhibition of LP neurons. Stimulation of the PAG induced marked inhibition of the firing of neurons in all three thalamic nuclei. No differences were found between cats anesthetized with ketamine or pentobarbital.

Original languageEnglish
Pages (from-to)698-705
Number of pages8
JournalExperimental Neurology
Issue number3
Publication statusPublished - 1983


ASJC Scopus subject areas

  • Neuroscience(all)
  • Neurology

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