Abstract
To evaluate the impact of influenza C (ICV) infection in children with community-acquired pneumonia (CAP), all of the children consecutively seen during 4 influenza seasons with respiratory symptoms and radiographically confirmed CAP were prospectively evaluated. ICV was identified in the respiratory secretions of five of 391 patients (1·3%). In children with ICV-associated CAP, clinical data were similar to those observed in children with IAV-associated CAP and worse than those observed in children with IBV-associated. The phylogenetic tree showed that the sequenced strains clustered in two of the six ICV lineages. These findings highlight that ICV can be a cause of CAP of children and that this can be severe enough to require hospitalization.
| Original language | English |
|---|---|
| Pages (from-to) | 999-1003 |
| Number of pages | 5 |
| Journal | Influenza and other Respiratory Viruses |
| Volume | 7 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Nov 2013 |
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Keywords
- Children
- Community-acquired pneumonia
- Influenza
- Influenza C
- Influenza C virus
ASJC Scopus subject areas
- Infectious Diseases
- Pulmonary and Respiratory Medicine
- Public Health, Environmental and Occupational Health
- Epidemiology
Cite this
Influenza C virus-associated community-acquired pneumonia in children. / Principi, Nicola; Scala, Alessia; Daleno, Cristina; Esposito, Susanna.
In: Influenza and other Respiratory Viruses, Vol. 7, No. 6, 11.2013, p. 999-1003.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Influenza C virus-associated community-acquired pneumonia in children
AU - Principi, Nicola
AU - Scala, Alessia
AU - Daleno, Cristina
AU - Esposito, Susanna
PY - 2013/11
Y1 - 2013/11
N2 - To evaluate the impact of influenza C (ICV) infection in children with community-acquired pneumonia (CAP), all of the children consecutively seen during 4 influenza seasons with respiratory symptoms and radiographically confirmed CAP were prospectively evaluated. ICV was identified in the respiratory secretions of five of 391 patients (1·3%). In children with ICV-associated CAP, clinical data were similar to those observed in children with IAV-associated CAP and worse than those observed in children with IBV-associated. The phylogenetic tree showed that the sequenced strains clustered in two of the six ICV lineages. These findings highlight that ICV can be a cause of CAP of children and that this can be severe enough to require hospitalization.
AB - To evaluate the impact of influenza C (ICV) infection in children with community-acquired pneumonia (CAP), all of the children consecutively seen during 4 influenza seasons with respiratory symptoms and radiographically confirmed CAP were prospectively evaluated. ICV was identified in the respiratory secretions of five of 391 patients (1·3%). In children with ICV-associated CAP, clinical data were similar to those observed in children with IAV-associated CAP and worse than those observed in children with IBV-associated. The phylogenetic tree showed that the sequenced strains clustered in two of the six ICV lineages. These findings highlight that ICV can be a cause of CAP of children and that this can be severe enough to require hospitalization.
KW - Children
KW - Community-acquired pneumonia
KW - Influenza
KW - Influenza C
KW - Influenza C virus
UR - http://www.scopus.com/inward/record.url?scp=84887211025&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887211025&partnerID=8YFLogxK
U2 - 10.1111/irv.12062
DO - 10.1111/irv.12062
M3 - Article
VL - 7
SP - 999
EP - 1003
JO - Influenza and other Respiratory Viruses
JF - Influenza and other Respiratory Viruses
SN - 1750-2640
IS - 6
ER -