Influenza C virus-associated community-acquired pneumonia in children

Nicola Principi, Alessia Scala, Cristina Daleno, Susanna Esposito

Research output: Contribution to journalArticlepeer-review

Abstract

To evaluate the impact of influenza C (ICV) infection in children with community-acquired pneumonia (CAP), all of the children consecutively seen during 4 influenza seasons with respiratory symptoms and radiographically confirmed CAP were prospectively evaluated. ICV was identified in the respiratory secretions of five of 391 patients (1·3%). In children with ICV-associated CAP, clinical data were similar to those observed in children with IAV-associated CAP and worse than those observed in children with IBV-associated. The phylogenetic tree showed that the sequenced strains clustered in two of the six ICV lineages. These findings highlight that ICV can be a cause of CAP of children and that this can be severe enough to require hospitalization.

Original languageEnglish
Pages (from-to)999-1003
Number of pages5
JournalInfluenza and other Respiratory Viruses
Volume7
Issue number6
DOIs
Publication statusPublished - Nov 2013

Keywords

  • Children
  • Community-acquired pneumonia
  • Influenza
  • Influenza C
  • Influenza C virus

ASJC Scopus subject areas

  • Infectious Diseases
  • Pulmonary and Respiratory Medicine
  • Public Health, Environmental and Occupational Health
  • Epidemiology

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