Abstract
In this chapter, an information geometric approach to survival analysis has been described. It shows how a neural network can be used to model the probability of failure of a system, and how it can be trained by minimizing a suitable divergence functional in a Bayesian framework. By using the trained network, minimization of the same divergence functional allows for fast, efficient, and exact feature selection. The performance of the algorithms has been illustrated on some datasets. In this chapter, a novel approach to survival analysis has been presented. Neural network architecture has been defined and trained according to information geometric principles. The same concepts are applied to exploit the geometric structure of the network and an algorithm is formulated which efficiently solves the feature selection problem. The proposed approach does not make any assumption on the form of the survival process, and does not use discretizations or piecewise approximations as other neural network approaches to survival analysis do.
Original language | English |
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Title of host publication | Outcome Prediction in Cancer |
Publisher | Elsevier |
Pages | 171-189 |
Number of pages | 19 |
ISBN (Print) | 9780444528551 |
DOIs | |
Publication status | Published - 2007 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)