Abstract
In CT colonography (CTC), orally administered positivecontrast fecal-tagging agents can cause artificial elevation of the observed radiodensity of adjacent soft tissue. Such pseudo-enhancement makes it challenging to differentiate polyps and folds reliably from tagged materials, and it is also present in dual-energy CTC (DE-CTC).We developed a method that corrects for pseudo-enhancement on DE-CTC images without distorting the dual-energy information contained in the data. A pilot study was performed to evaluate the effect of the method visually and quantitatively by use of clinical non-cathartic low-dose DE-CTC data from 10 patients including 13 polyps covered partially or completely by iodine-based fecal tagging. The results indicate that the proposed method can be used to reduce the pseudo-enhancement distortion of DE-CTC images without losing material-specific dual-energy information. The method has potential application in improving the accuracy of automated image-processing applications, such as computer-aided detection and virtual bowel cleansing in CTC.
| Original language | English |
|---|---|
| Title of host publication | Abdominal Imaging: Computational and Clinical Applications - 6th International Workshop, ABDI 2014 held in conjunction with MICCAI 2014 |
| Publisher | Springer Verlag |
| Pages | 159-168 |
| Number of pages | 10 |
| Volume | 8676 |
| ISBN (Print) | 9783319136912 |
| DOIs | |
| Publication status | Published - 2014 |
| Event | 6th International Workshop on Abdominal Imaging: Computational and Clinical Applications, ABDI 2014 held in conjunction with 17th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2014 - Cambridge, United States Duration: Sep 14 2014 → Sep 14 2014 |
Publication series
| Name | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
|---|---|
| Volume | 8676 |
| ISSN (Print) | 03029743 |
| ISSN (Electronic) | 16113349 |
Other
| Other | 6th International Workshop on Abdominal Imaging: Computational and Clinical Applications, ABDI 2014 held in conjunction with 17th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2014 |
|---|---|
| Country | United States |
| City | Cambridge |
| Period | 9/14/14 → 9/14/14 |
Fingerprint
Keywords
- CT colonography
- Dual-energy CT
- Pseudo-enhancement
- Virtual colonoscopy
ASJC Scopus subject areas
- Computer Science(all)
- Theoretical Computer Science
Cite this
Information-preserving pseudo-enhancement correction for non-cathartic low-dose dual-energy CT colonography. / Näppi, Janne J.; Tachibana, Rie; Regge, Daniele; Yoshida, Hiroyuki.
Abdominal Imaging: Computational and Clinical Applications - 6th International Workshop, ABDI 2014 held in conjunction with MICCAI 2014. Vol. 8676 Springer Verlag, 2014. p. 159-168 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 8676).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Information-preserving pseudo-enhancement correction for non-cathartic low-dose dual-energy CT colonography
AU - Näppi, Janne J.
AU - Tachibana, Rie
AU - Regge, Daniele
AU - Yoshida, Hiroyuki
PY - 2014
Y1 - 2014
N2 - In CT colonography (CTC), orally administered positivecontrast fecal-tagging agents can cause artificial elevation of the observed radiodensity of adjacent soft tissue. Such pseudo-enhancement makes it challenging to differentiate polyps and folds reliably from tagged materials, and it is also present in dual-energy CTC (DE-CTC).We developed a method that corrects for pseudo-enhancement on DE-CTC images without distorting the dual-energy information contained in the data. A pilot study was performed to evaluate the effect of the method visually and quantitatively by use of clinical non-cathartic low-dose DE-CTC data from 10 patients including 13 polyps covered partially or completely by iodine-based fecal tagging. The results indicate that the proposed method can be used to reduce the pseudo-enhancement distortion of DE-CTC images without losing material-specific dual-energy information. The method has potential application in improving the accuracy of automated image-processing applications, such as computer-aided detection and virtual bowel cleansing in CTC.
AB - In CT colonography (CTC), orally administered positivecontrast fecal-tagging agents can cause artificial elevation of the observed radiodensity of adjacent soft tissue. Such pseudo-enhancement makes it challenging to differentiate polyps and folds reliably from tagged materials, and it is also present in dual-energy CTC (DE-CTC).We developed a method that corrects for pseudo-enhancement on DE-CTC images without distorting the dual-energy information contained in the data. A pilot study was performed to evaluate the effect of the method visually and quantitatively by use of clinical non-cathartic low-dose DE-CTC data from 10 patients including 13 polyps covered partially or completely by iodine-based fecal tagging. The results indicate that the proposed method can be used to reduce the pseudo-enhancement distortion of DE-CTC images without losing material-specific dual-energy information. The method has potential application in improving the accuracy of automated image-processing applications, such as computer-aided detection and virtual bowel cleansing in CTC.
KW - CT colonography
KW - Dual-energy CT
KW - Pseudo-enhancement
KW - Virtual colonoscopy
UR - http://www.scopus.com/inward/record.url?scp=84927594550&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84927594550&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-13692-9_15
DO - 10.1007/978-3-319-13692-9_15
M3 - Conference contribution
SN - 9783319136912
VL - 8676
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 159
EP - 168
BT - Abdominal Imaging: Computational and Clinical Applications - 6th International Workshop, ABDI 2014 held in conjunction with MICCAI 2014
PB - Springer Verlag
ER -