Information transfer through the spontaneous baroreflex in healthy humans

A. Porta, A. M. Catai, A. C M Takahashi, V. Magagnin, T. Bassani, E. Tobaldini, N. Montano

Research output: Contribution to journalArticlepeer-review


Objectives: This study assesses the information transfer through the spontaneous baroreflex (i.e. through the pathway linking systolic arterial pressure to heart period) during an experimental condition soliciting baroreflex (i.e. head-up tilt). Methods: The information transfer was calculated as the conditional entropy of heart period given systolic arterial pressure using a mutual neighbor approach and uniform quantization. The information transfer was monitored as a function of the forecasting time k. Results: We found that during head-up tilt the information transfer at k = 0 decreased but the rate of rise of information transfer as a function of k was faster. Conclusions: We suggest that the characterization of the information transfer from systolic arterial pressure to heart period might complement the traditional characterization of the spontaneous baroreflex based on transfer function analysis.

Original languageEnglish
Pages (from-to)506-510
Number of pages5
JournalMethods of Information in Medicine
Issue number5
Publication statusPublished - 2010


  • Autonomic nervous system
  • Baroreflex
  • Cardiovascular control
  • Cross-conditional entropy
  • Information transfer

ASJC Scopus subject areas

  • Health Informatics
  • Health Information Management
  • Advanced and Specialised Nursing


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