Infrequent finding of metallo-β-lactamase VIM-2 in carbapenem-resistant Pseudomonas aeruginosa strains from Croatia

Sanda Sardelic, Branka Bedenic, Céline Colinon-Dupuich, Stjepan Orhanovic, Zrinka Bosnjak, Vanda Plecko, Benoit Cournoyer, Gian Maria Rossolini

Research output: Contribution to journalArticlepeer-review

Abstract

One hundred sixty-nine nonreplicate imipenem-resistant Pseudomonas aeruginosa strains isolated in a large hospital on the coastal region of Croatia were studied. The most active antibiotics were colistin and amikacin. Most of the isolates were multiresistant. The most prevalent serotype was O12, followed by O11. Six strains carried the bla VIM-2 gene located in a novel class 1 integron composed in its variable part of the bla VIM-2- bla oxa-10-ΔqacF-aacA4 genes. Metallo-β-lactamase-producing strains belonged to sequence types ST235 and ST111.

Original languageEnglish
Pages (from-to)2746-2749
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume56
Issue number5
DOIs
Publication statusPublished - May 2012

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology
  • Infectious Diseases

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