Inheritance of the rDNA spacer in D. melanogaster

E. Boncinelli, A. Borghese, F. Graziani, G. La Mantia, A. Manzi, C. Mariani, A. Simeone

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We studied the organization of rDNA spacer sequences within several rDNA loci in D. melanogaster. Every locus showed many discrete length classes of rDNA spacer, ranging from 2.4 kb to about 20 kb. Different loci show characteristic distributions of spacers within the various length classes. Using this molecular characteristic as a genetic marker, segregation, recombination and occurrence of unequal crossing-over were studied. The rDNA loci segregated with a Mendelian pattern; interhomologous recombination events occurred at the expected rate; conversely unequal crossing-over within the rDNA locus appears not to be as frequent as expected.

Original languageEnglish
Pages (from-to)370-374
Number of pages5
JournalMGG Molecular & General Genetics
Volume189
Issue number3
DOIs
Publication statusPublished - Mar 1983

Fingerprint

Ribosomal DNA
Genetic Recombination
Genetic Markers

ASJC Scopus subject areas

  • Genetics

Cite this

Boncinelli, E., Borghese, A., Graziani, F., La Mantia, G., Manzi, A., Mariani, C., & Simeone, A. (1983). Inheritance of the rDNA spacer in D. melanogaster. MGG Molecular & General Genetics, 189(3), 370-374. https://doi.org/10.1007/BF00325897

Inheritance of the rDNA spacer in D. melanogaster. / Boncinelli, E.; Borghese, A.; Graziani, F.; La Mantia, G.; Manzi, A.; Mariani, C.; Simeone, A.

In: MGG Molecular & General Genetics, Vol. 189, No. 3, 03.1983, p. 370-374.

Research output: Contribution to journalArticle

Boncinelli, E, Borghese, A, Graziani, F, La Mantia, G, Manzi, A, Mariani, C & Simeone, A 1983, 'Inheritance of the rDNA spacer in D. melanogaster', MGG Molecular & General Genetics, vol. 189, no. 3, pp. 370-374. https://doi.org/10.1007/BF00325897
Boncinelli E, Borghese A, Graziani F, La Mantia G, Manzi A, Mariani C et al. Inheritance of the rDNA spacer in D. melanogaster. MGG Molecular & General Genetics. 1983 Mar;189(3):370-374. https://doi.org/10.1007/BF00325897
Boncinelli, E. ; Borghese, A. ; Graziani, F. ; La Mantia, G. ; Manzi, A. ; Mariani, C. ; Simeone, A. / Inheritance of the rDNA spacer in D. melanogaster. In: MGG Molecular & General Genetics. 1983 ; Vol. 189, No. 3. pp. 370-374.
@article{870dec83e64a4382bd41a287fc9ed095,
title = "Inheritance of the rDNA spacer in D. melanogaster",
abstract = "We studied the organization of rDNA spacer sequences within several rDNA loci in D. melanogaster. Every locus showed many discrete length classes of rDNA spacer, ranging from 2.4 kb to about 20 kb. Different loci show characteristic distributions of spacers within the various length classes. Using this molecular characteristic as a genetic marker, segregation, recombination and occurrence of unequal crossing-over were studied. The rDNA loci segregated with a Mendelian pattern; interhomologous recombination events occurred at the expected rate; conversely unequal crossing-over within the rDNA locus appears not to be as frequent as expected.",
author = "E. Boncinelli and A. Borghese and F. Graziani and {La Mantia}, G. and A. Manzi and C. Mariani and A. Simeone",
year = "1983",
month = "3",
doi = "10.1007/BF00325897",
language = "English",
volume = "189",
pages = "370--374",
journal = "Molecular Genetics and Genomics",
issn = "1617-4615",
publisher = "Springer Verlag",
number = "3",

}

TY - JOUR

T1 - Inheritance of the rDNA spacer in D. melanogaster

AU - Boncinelli, E.

AU - Borghese, A.

AU - Graziani, F.

AU - La Mantia, G.

AU - Manzi, A.

AU - Mariani, C.

AU - Simeone, A.

PY - 1983/3

Y1 - 1983/3

N2 - We studied the organization of rDNA spacer sequences within several rDNA loci in D. melanogaster. Every locus showed many discrete length classes of rDNA spacer, ranging from 2.4 kb to about 20 kb. Different loci show characteristic distributions of spacers within the various length classes. Using this molecular characteristic as a genetic marker, segregation, recombination and occurrence of unequal crossing-over were studied. The rDNA loci segregated with a Mendelian pattern; interhomologous recombination events occurred at the expected rate; conversely unequal crossing-over within the rDNA locus appears not to be as frequent as expected.

AB - We studied the organization of rDNA spacer sequences within several rDNA loci in D. melanogaster. Every locus showed many discrete length classes of rDNA spacer, ranging from 2.4 kb to about 20 kb. Different loci show characteristic distributions of spacers within the various length classes. Using this molecular characteristic as a genetic marker, segregation, recombination and occurrence of unequal crossing-over were studied. The rDNA loci segregated with a Mendelian pattern; interhomologous recombination events occurred at the expected rate; conversely unequal crossing-over within the rDNA locus appears not to be as frequent as expected.

UR - http://www.scopus.com/inward/record.url?scp=24944434905&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=24944434905&partnerID=8YFLogxK

U2 - 10.1007/BF00325897

DO - 10.1007/BF00325897

M3 - Article

VL - 189

SP - 370

EP - 374

JO - Molecular Genetics and Genomics

JF - Molecular Genetics and Genomics

SN - 1617-4615

IS - 3

ER -