Inheritance of the rDNA spacer in D. melanogaster

E. Boncinelli, A. Borghese, F. Graziani, G. La Mantia, A. Manzi, C. Mariani, A. Simeone

Research output: Contribution to journalArticlepeer-review


We studied the organization of rDNA spacer sequences within several rDNA loci in D. melanogaster. Every locus showed many discrete length classes of rDNA spacer, ranging from 2.4 kb to about 20 kb. Different loci show characteristic distributions of spacers within the various length classes. Using this molecular characteristic as a genetic marker, segregation, recombination and occurrence of unequal crossing-over were studied. The rDNA loci segregated with a Mendelian pattern; interhomologous recombination events occurred at the expected rate; conversely unequal crossing-over within the rDNA locus appears not to be as frequent as expected.

Original languageEnglish
Pages (from-to)370-374
Number of pages5
JournalMGG Molecular & General Genetics
Issue number3
Publication statusPublished - Mar 1983

ASJC Scopus subject areas

  • Genetics


Dive into the research topics of 'Inheritance of the rDNA spacer in D. melanogaster'. Together they form a unique fingerprint.

Cite this