Inhibition of adipogenesis: A new job for the ER Ca2+ pool

Jacopo Meldolesi

Research output: Contribution to journalArticlepeer-review

Abstract

Adipogenesis is the process of differentiation of adipocytes from mesenchymal multipotent cells through adipocyte precursors. In this issue, a study by the groups of Opas and Michalak (Szabo, E., Y. Qiu, S. Baksh, M. Michalak, and M. Opas. 2008. J. Cell. Biol. 182:103-116) demonstrates that this process is repressed by increasing intracellular Ca2+, which, in turn, is dependent on the expression of calreticulin, the major Ca 2+-binding protein of the endoplasmic reticulum lumen.

Original languageEnglish
Pages (from-to)11-13
Number of pages3
JournalJournal of Cell Biology
Volume182
Issue number1
DOIs
Publication statusPublished - Jul 14 2008

ASJC Scopus subject areas

  • Cell Biology

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