Inhibition of auditory cortical responses to ipsilateral stimuli during dichotic listening: Evidence from magnetoencephalography

Alfredo Brancucci, Claudio Babiloni, Fabio Babiloni, Silvana Galderisi, Armida Mucci, Franca Tecchio, Filippo Zappasodi, Vittorio Pizzella, Gian Luca Romani, Paolo Maria Rossini

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

The present magnetoencephalography (MEG) study on auditory evoked magnetic fields (AEFs) was aimed at verifying whether during dichotic listening the contralateral auditory pathway inhibits the ipsilateral one, as suggested by behavioural and patient studies. Ten healthy subjects were given a randomized series of three complex tones (261, 293 and 391 Hz, 500 ms duration), which were delivered monotically and dichotically with different intensities [60, 70 or 80 dBA (audio decibels)]. MEG data were recorded from the right auditory cortex. Results showed that the M100 amplitude over the right auditory cortex increased progressively when tones of increasing intensity were provided at the ipsilateral (right) ear. This effect on M100 was abolished when a concurrent tone of constant intensity was delivered dichotically at the contralateral (left) ear, suggesting that the contralateral pathway inhibited the ipsilateral one. The ipsilateral inhibition was present only when the contralateral tone fundamental frequency was similar to the ipsilateral tone. It was proposed that the occlusion mechanism would be exerted in cortical auditory areas as the dichotic effects were observed at M100 but not M50 component. This is the first evidence showing a neurophysiological inhibition driven by the contralateral auditory pathway over the ipsilateral one during dichotic listening.

Original languageEnglish
Pages (from-to)2329-2336
Number of pages8
JournalEuropean Journal of Neuroscience
Volume19
Issue number8
DOIs
Publication statusPublished - Apr 2004

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Magnetoencephalography
Auditory Cortex
Auditory Pathways
Ear
Magnetic Fields
Healthy Volunteers

Keywords

  • Auditory evoked magnetic fields (AEFs)
  • Auditory pathways
  • Complex tones
  • M100
  • M50
  • Right auditory cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Inhibition of auditory cortical responses to ipsilateral stimuli during dichotic listening : Evidence from magnetoencephalography. / Brancucci, Alfredo; Babiloni, Claudio; Babiloni, Fabio; Galderisi, Silvana; Mucci, Armida; Tecchio, Franca; Zappasodi, Filippo; Pizzella, Vittorio; Romani, Gian Luca; Rossini, Paolo Maria.

In: European Journal of Neuroscience, Vol. 19, No. 8, 04.2004, p. 2329-2336.

Research output: Contribution to journalArticle

Brancucci, A, Babiloni, C, Babiloni, F, Galderisi, S, Mucci, A, Tecchio, F, Zappasodi, F, Pizzella, V, Romani, GL & Rossini, PM 2004, 'Inhibition of auditory cortical responses to ipsilateral stimuli during dichotic listening: Evidence from magnetoencephalography', European Journal of Neuroscience, vol. 19, no. 8, pp. 2329-2336. https://doi.org/10.1111/j.0953-816X.2004.03302.x
Brancucci, Alfredo ; Babiloni, Claudio ; Babiloni, Fabio ; Galderisi, Silvana ; Mucci, Armida ; Tecchio, Franca ; Zappasodi, Filippo ; Pizzella, Vittorio ; Romani, Gian Luca ; Rossini, Paolo Maria. / Inhibition of auditory cortical responses to ipsilateral stimuli during dichotic listening : Evidence from magnetoencephalography. In: European Journal of Neuroscience. 2004 ; Vol. 19, No. 8. pp. 2329-2336.
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