Inhibitory effect of calcitonin on growth hormone and insulin secretion in man

Luigi Cantalamessa; Anna Catania; Eugenio Reschini; Maddalena Peracchi

doi:10.1016/0026-0495(78)90143-9

Inhibitory effect of calcitonin on growth hormone and insulin secretion in man

Luigi Cantalamessa, Anna Catania, Eugenio Reschini, Maddalena Peracchi

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

The effect of calcitonin administration on basal and arginine-stimulated growth hormone and insulin plasma levels was investigated. The intramuscular injection of synthetic salmon calcitonin (100 U MRC) in five normal subjects produced a significant decrease (p <0.05) in insulin concentration. The same amount of calcitonin given 15 min before an arginine infusion test in seven normal subjects significantly reduced the response of growth hormone (p <0.025) and insulin (p <0.005) to the stimulus.

Original language	English
Pages (from-to)	987-992
Number of pages	6
Journal	Metabolism
Volume	27
Issue number	8
DOIs	https://doi.org/10.1016/0026-0495(78)90143-9
Publication status	Published - 1978

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism

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abstract = "The effect of calcitonin administration on basal and arginine-stimulated growth hormone and insulin plasma levels was investigated. The intramuscular injection of synthetic salmon calcitonin (100 U MRC) in five normal subjects produced a significant decrease (p <0.05) in insulin concentration. The same amount of calcitonin given 15 min before an arginine infusion test in seven normal subjects significantly reduced the response of growth hormone (p <0.025) and insulin (p <0.005) to the stimulus.",

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AU - Catania, Anna

AU - Reschini, Eugenio

AU - Peracchi, Maddalena

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AB - The effect of calcitonin administration on basal and arginine-stimulated growth hormone and insulin plasma levels was investigated. The intramuscular injection of synthetic salmon calcitonin (100 U MRC) in five normal subjects produced a significant decrease (p <0.05) in insulin concentration. The same amount of calcitonin given 15 min before an arginine infusion test in seven normal subjects significantly reduced the response of growth hormone (p <0.025) and insulin (p <0.005) to the stimulus.

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