Initial multicenter experience with a novel distal protection filter during carotid artery stent implantation

Eberhard Grube, Antonio Colombo, Eugen Hauptmann, Hugo Londero, Nicolaus Reifart, Ulrich Gerckens, Gregg W. Stone

Research output: Contribution to journalArticlepeer-review


Atheroembolization resulting in transient or permanent neurologic impairment is the most common complication of catheter-based percutaneous carotid artery intervention. Protection of the distal cerebral Vasculature during carotid stent implantation may enhance procedural safety. Carotid stent implantation with distal cerebral protection using the FilterWire EX was performed in 35 consecutive patients undergoing 36 procedures at six centers. The FilterWire was delivered and deployed successfully in all 36 cases, and embolic material was retrieved from 74% of procedures. The 30-day rate of major adverse events (death, major or minor stroke) was 0%. Transient ipsilateral periprocedural neurologic ischemia developed in two patients (5.7%), both resolving within 30 min. Distal cerebral protection with the FilterWire during carotid stenting is feasible and safe, results in capture and extraction of atheroembolic debris in the majority of patients while affording uninterrupted cerebral perfusion, and in this initial multicenter experience was associated with a high rate of procedural success without major complications.

Original languageEnglish
Pages (from-to)139-146
Number of pages8
JournalCatheterization and Cardiovascular Interventions
Issue number2
Publication statusPublished - Feb 1 2003


  • Carotid disease
  • Distal protection
  • Emboli
  • Filters
  • Stenting

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging


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