Initial results from a PET/planar small animal imaging system

S. Siegel, J. J. Vaquero, L. Aloj, J. Seidel, E. Jagoda, W. R. Gandler, W. C. Eckelman, M. V. Green

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positron-emitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. In projection mode, the animal is placed within the 55 mm × 45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from lines-of-response falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of semi-static tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically altered mice.

Original languageEnglish
Title of host publicationIEEE Nuclear Science Symposium and Medical Imaging Conference
PublisherIEEE
Pages1274-1276
Number of pages3
Volume2
ISBN (Print)0780350227
Publication statusPublished - 1999
EventProceedings of the 1998 IEEE Nuclear Science Symposium Conference Record - Toronto, Que, Can
Duration: Nov 8 1998Nov 14 1998

Other

OtherProceedings of the 1998 IEEE Nuclear Science Symposium Conference Record
CityToronto, Que, Can
Period11/8/9811/14/98

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

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  • Cite this

    Siegel, S., Vaquero, J. J., Aloj, L., Seidel, J., Jagoda, E., Gandler, W. R., Eckelman, W. C., & Green, M. V. (1999). Initial results from a PET/planar small animal imaging system. In IEEE Nuclear Science Symposium and Medical Imaging Conference (Vol. 2, pp. 1274-1276). IEEE.