Abstract
A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positron-emitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. In projection mode, the animal is placed within the 55 mm × 45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from lines-of-response falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of semi-static tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically altered mice.
| Original language | English |
|---|---|
| Title of host publication | IEEE Nuclear Science Symposium and Medical Imaging Conference |
| Publisher | IEEE |
| Pages | 1274-1276 |
| Number of pages | 3 |
| Volume | 2 |
| ISBN (Print) | 0780350227 |
| Publication status | Published - 1999 |
| Event | Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record - Toronto, Que, Can Duration: Nov 8 1998 → Nov 14 1998 |
Other
| Other | Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record |
|---|---|
| City | Toronto, Que, Can |
| Period | 11/8/98 → 11/14/98 |
ASJC Scopus subject areas
- Computer Vision and Pattern Recognition
- Industrial and Manufacturing Engineering