Abstract
A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positron-emitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. In projection mode, the animal is placed within the 55 mm × 45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from lines-of-response falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of semi-static tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically altered mice.
Original language | English |
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Title of host publication | IEEE Nuclear Science Symposium and Medical Imaging Conference |
Publisher | IEEE |
Pages | 1274-1276 |
Number of pages | 3 |
Volume | 2 |
ISBN (Print) | 0780350227 |
Publication status | Published - 1999 |
Event | Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record - Toronto, Que, Can Duration: Nov 8 1998 → Nov 14 1998 |
Other
Other | Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record |
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City | Toronto, Que, Can |
Period | 11/8/98 → 11/14/98 |
ASJC Scopus subject areas
- Computer Vision and Pattern Recognition
- Industrial and Manufacturing Engineering