Initial results from a PET/planar small animal imaging system

S. Siegel; J. J. Vaquero; L. Aloj; J. Seidel; E. Jagoda; W. R. Gandler; W. C. Eckelman; M. V. Green

Initial results from a PET/planar small animal imaging system

S. Siegel, J. J. Vaquero, L. Aloj, J. Seidel, E. Jagoda, W. R. Gandler, W. C. Eckelman, M. V. Green

Istituto Nazionale Tumori Fondazione G. Pascale

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positron-emitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. In projection mode, the animal is placed within the 55 mm × 45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from lines-of-response falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of semi-static tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically altered mice.

Original language	English
Title of host publication	IEEE Nuclear Science Symposium and Medical Imaging Conference
Publisher	IEEE
Pages	1274-1276
Number of pages	3
Volume	2
ISBN (Print)	0780350227
Publication status	Published - 1999
Event	Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record - Toronto, Que, Can Duration: Nov 8 1998 → Nov 14 1998

Other

Other	Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record
City	Toronto, Que, Can
Period	11/8/98 → 11/14/98

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Industrial and Manufacturing Engineering

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Siegel, S., Vaquero, J. J., Aloj, L., Seidel, J., Jagoda, E., Gandler, W. R., Eckelman, W. C., & Green, M. V. (1999). Initial results from a PET/planar small animal imaging system. In IEEE Nuclear Science Symposium and Medical Imaging Conference (Vol. 2, pp. 1274-1276). IEEE.

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title = "Initial results from a PET/planar small animal imaging system",

abstract = "A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positron-emitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. In projection mode, the animal is placed within the 55 mm × 45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from lines-of-response falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of semi-static tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically altered mice.",

author = "S. Siegel and Vaquero, {J. J.} and L. Aloj and J. Seidel and E. Jagoda and Gandler, {W. R.} and Eckelman, {W. C.} and Green, {M. V.}",

year = "1999",

language = "English",

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volume = "2",

pages = "1274--1276",

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AU - Siegel, S.

AU - Vaquero, J. J.

AU - Aloj, L.

AU - Seidel, J.

AU - Jagoda, E.

AU - Gandler, W. R.

AU - Eckelman, W. C.

AU - Green, M. V.

PY - 1999

Y1 - 1999

N2 - A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positron-emitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. In projection mode, the animal is placed within the 55 mm × 45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from lines-of-response falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of semi-static tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically altered mice.

AB - A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positron-emitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. In projection mode, the animal is placed within the 55 mm × 45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from lines-of-response falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of semi-static tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically altered mice.

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