Innovative techniques in evaluating the esophagus; imaging of esophageal morphology and function; and drugs for esophageal disease

Helmut Neumann, Markus F. Neurath, Michael Vieth, Frederiek M. Lever, Gert J. Meijer, Irene M. Lips, Barry P. Mcmahon, J. P. Ruurda, R. van Hillegersberg, P. Siersema, Marc S. Levine, Martina Scharitzer, Peter Pokieser, Frank Zerbib, Vincenzo Savarino, Patrizia Zentilin, Edoardo Savarino, Walter W. Chan

Research output: Contribution to journalArticle

Abstract

This paper reporting on techniques for esophageal evaluation and imaging and drugs for esophageal disease includes commentaries on endoscopy techniques including dye-based high-resolution and dye-less high-definition endoscopy; the shift from CT to MRI guidance in tumor delineation for radiation therapy; the role of functional lumen imaging in measuring esophageal distensibility; electrical stimulation of the lower esophageal sphincter (LES) as an alternative to fundoduplication for treatment of gastroesophageal reflux disease (GERD); the morphological findings of reflux esophagitis and esophageal dysmotility on double-contrast esophagography; the value of videofluoroscopy in assessing protecting mechanisms in patients with chronic reflux or swallowing disorders; targeting visceral hypersensitivity in the treatment of refractory GERD; and the symptoms and treatments of nighttime reflux and nocturnal acid breakthrough (NAB).

Original languageEnglish
Pages (from-to)11-28
Number of pages18
JournalAnnals of the New York Academy of Sciences
Volume1300
Issue number1
DOIs
Publication statusPublished - Oct 2013

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Keywords

  • Endoscopy
  • EndoStim
  • FLIP
  • GERD
  • Nighttime breakthrough
  • PPI
  • Swallowing
  • Videofluoroscopy

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Cite this

Neumann, H., Neurath, M. F., Vieth, M., Lever, F. M., Meijer, G. J., Lips, I. M., Mcmahon, B. P., Ruurda, J. P., van Hillegersberg, R., Siersema, P., Levine, M. S., Scharitzer, M., Pokieser, P., Zerbib, F., Savarino, V., Zentilin, P., Savarino, E., & Chan, W. W. (2013). Innovative techniques in evaluating the esophagus; imaging of esophageal morphology and function; and drugs for esophageal disease. Annals of the New York Academy of Sciences, 1300(1), 11-28. https://doi.org/10.1111/nyas.12233