ins(6;1) in a patient with congenital leukemia

Raffaele Sansone, Mario Sessarego, Riccardo Haupt, Maria Luisa Garré, Paolo Strigini

Research output: Contribution to journalArticle

Abstract

Q- and C-banded karyotypes of leukemic cells of a patient with congenital acute lymphoblastic leukemia showed the karyotype: 46,XX,ins(6;1)(p21;p13p36). This rearrangement is unusual, and the breakpoints on chromosome 1 are interestingly close to known cellular oncogenes (N-ras, fgr, src-2) and to a putative antioncogene.

Original languageEnglish
Pages (from-to)19-22
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume37
Issue number1
DOIs
Publication statusPublished - 1989

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ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

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