ins(6;1) in a patient with congenital leukemia

Raffaele Sansone, Mario Sessarego, Riccardo Haupt, Maria Luisa Garré, Paolo Strigini

Research output: Contribution to journal › Article

3 Citations (Scopus)

Abstract

Q- and C-banded karyotypes of leukemic cells of a patient with congenital acute lymphoblastic leukemia showed the karyotype: 46,XX,ins(6;1)(p21;p13p36). This rearrangement is unusual, and the breakpoints on chromosome 1 are interestingly close to known cellular oncogenes (N-ras, fgr, src-2) and to a putative antioncogene.

Original languageEnglish
Pages (from-to)19-22
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume37
Issue number1
DOIs
Publication statusPublished - 1989

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Karyotype
Leukemia
ras Genes
Chromosomes, Human, Pair 1
Tumor Suppressor Genes
Precursor Cell Lymphoblastic Leukemia-Lymphoma

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

Cite this

ins(6;1) in a patient with congenital leukemia. / Sansone, Raffaele; Sessarego, Mario; Haupt, Riccardo; Garré, Maria Luisa; Strigini, Paolo.

In: Cancer Genetics and Cytogenetics, Vol. 37, No. 1, 1989, p. 19-22.

Research output: Contribution to journal › Article

Sansone, R, Sessarego, M, Haupt, R, Garré, ML & Strigini, P 1989, 'ins(6;1) in a patient with congenital leukemia', Cancer Genetics and Cytogenetics, vol. 37, no. 1, pp. 19-22. https://doi.org/10.1016/0165-4608(89)90069-1
Sansone R, Sessarego M, Haupt R, Garré ML, Strigini P. ins(6;1) in a patient with congenital leukemia. Cancer Genetics and Cytogenetics. 1989;37(1):19-22. https://doi.org/10.1016/0165-4608(89)90069-1
Sansone, Raffaele ; Sessarego, Mario ; Haupt, Riccardo ; Garré, Maria Luisa ; Strigini, Paolo. / ins(6;1) in a patient with congenital leukemia. In: Cancer Genetics and Cytogenetics. 1989 ; Vol. 37, No. 1. pp. 19-22.
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