ins(6;1) in a patient with congenital leukemia

Raffaele Sansone, Mario Sessarego, Riccardo Haupt, Maria Luisa Garré, Paolo Strigini

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Q- and C-banded karyotypes of leukemic cells of a patient with congenital acute lymphoblastic leukemia showed the karyotype: 46,XX,ins(6;1)(p21;p13p36). This rearrangement is unusual, and the breakpoints on chromosome 1 are interestingly close to known cellular oncogenes (N-ras, fgr, src-2) and to a putative antioncogene.

Original languageEnglish
Pages (from-to)19-22
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume37
Issue number1
DOIs
Publication statusPublished - 1989

Fingerprint

Karyotype
Leukemia
ras Genes
Chromosomes, Human, Pair 1
Tumor Suppressor Genes
Precursor Cell Lymphoblastic Leukemia-Lymphoma

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

Cite this

ins(6;1) in a patient with congenital leukemia. / Sansone, Raffaele; Sessarego, Mario; Haupt, Riccardo; Garré, Maria Luisa; Strigini, Paolo.

In: Cancer Genetics and Cytogenetics, Vol. 37, No. 1, 1989, p. 19-22.

Research output: Contribution to journalArticle

Sansone, Raffaele ; Sessarego, Mario ; Haupt, Riccardo ; Garré, Maria Luisa ; Strigini, Paolo. / ins(6;1) in a patient with congenital leukemia. In: Cancer Genetics and Cytogenetics. 1989 ; Vol. 37, No. 1. pp. 19-22.
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