ins(6;1) in a patient with congenital leukemia

Raffaele Sansone; Mario Sessarego; Riccardo Haupt; Maria Luisa Garré; Paolo Strigini

doi:10.1016/0165-4608(89)90069-1

ins(6;1) in a patient with congenital leukemia

Raffaele Sansone, Mario Sessarego, Riccardo Haupt, Maria Luisa Garré, Paolo Strigini

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article

Abstract

Q- and C-banded karyotypes of leukemic cells of a patient with congenital acute lymphoblastic leukemia showed the karyotype: 46,XX,ins(6;1)(p21;p13p36). This rearrangement is unusual, and the breakpoints on chromosome 1 are interestingly close to known cellular oncogenes (N-ras, fgr, src-2) and to a putative antioncogene.

Original language	English
Pages (from-to)	19-22
Number of pages	4
Journal	Cancer Genetics and Cytogenetics
Volume	37
Issue number	1
DOIs	https://doi.org/10.1016/0165-4608(89)90069-1
Publication status	Published - 1989

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ASJC Scopus subject areas

Cancer Research
Genetics
Molecular Biology

Cite this

Sansone, R., Sessarego, M., Haupt, R., Garré, M. L., & Strigini, P. (1989). ins(6;1) in a patient with congenital leukemia. Cancer Genetics and Cytogenetics, 37(1), 19-22. https://doi.org/10.1016/0165-4608(89)90069-1

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10.1016/0165-4608(89)90069-1