Insights from Cardiac Mechanics after Three Decades from Successfully Repaired Aortic Coarctation

Giorgio Faganello, Maurizio Fisicaro, Giulia Russo, Anita Iorio, Carmine Mazzone, Eliana Grande, Franco Humar, Antonella Cherubini, Claudio Pandullo, Giulia Barbati, Luigi Tarantini, Alessandra Benettoni, Marco Pozzi, Andrea Di Lenarda, Giovanni Cioffi

Research output: Contribution to journalArticlepeer-review

Abstract

Background and Aims: Patients who underwent a successful repair of the aortic coarctation show chronic hyperdynamic state and normal left ventricular (LV) geometry; however, there are few data regarding the LV systolic function in the long term. Accordingly, we assessed LV systolic mechanics and factors associated with LV systolic dysfunction (LVSD) in patients with repaired CoA. Methods: Clinical and echocardiographic data from 19 repaired CoA were analyzed 28 ± 13 years after surgery. Stress-corrected midwall shortening (sc-MS) and mitral annular peak systolic velocity (S′) were analyzed as indexes of LV circumferential and longitudinal systolic function, respectively. Echocardiographic data of CoA patients were compared with 19 patients matched for age and hypertension and 38 healthy controls. Sc-MS was considered impaired if

Original languageEnglish
Pages (from-to)254-261
Number of pages8
JournalCongenital Heart Disease
Volume11
Issue number3
DOIs
Publication statusPublished - May 1 2016

Keywords

  • Aortic Coarctation
  • Cardiac Function
  • Left Ventricular Systolic Function

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Radiology Nuclear Medicine and imaging

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