Insights in Hodgkin Lymphoma angiogenesis

Christian Marinaccio, Beatrice Nico, Eugenio Maiorano, Giorgina Specchia, Domenico Ribatti

Research output: Contribution to journalArticlepeer-review

Abstract

Angiogenesis is a hallmark of tumor growth and progression in solid and hematological malignancies. Different cellular components of the tumor microenvironment such as macrophages, mast cells, circulating endothelial cells and angiogenic factors, including vascular endothelial growth factor and its receptors are involved in the maintenance of Hodgkin Lymphoma. In this review article, we highlight relevant literature focusing on the relationships between angiogenesis and Hodgkin Lymphoma as well as discussing anti-angiogenic treatments in this malignancy.

Original languageEnglish
Pages (from-to)857-861
Number of pages5
JournalLeukemia Research
Volume38
Issue number8
DOIs
Publication statusPublished - 2014

Keywords

  • Angiogenesis
  • Anti-angiogenesis
  • Hodgkin Lymphoma
  • Tumor microenvironment

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology

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