Instrumentation

The remarkable innovation in molecular imaging and the introduction of advanced neurological diagnostic tools encouraged researchers and physicians in optimizing technological resources to approach brain diseases with increased accuracy of diagnosis. Computed tomography (CT), positron emission tomography (PET), and magnetic resonance (MR) imaging provide different and complementary information with both advantages and disadvantages. PET gives metabolic and molecular data, while CT offers high spatial resolution fiving detailed information at anatomical level, and MR enables investigation at morphological and functional levels also allowing diffusion imaging and spectroscopy [1]. In the attempt to overcome the limitations of stand-alone imaging methods, different modality combinations have been introduced.