Abstract
Purpose of Review: Radio therapy, alone or in combination with surgery and/or chemotherapy, is commonly used to treat a variety of neoplasms, resulting in effective local tumor control. Unfortunately radiation therapy can also change the structure of the skeletal system, leading to edema, vascular congestion, areas of hemorrhage, loss of cellularity, focal bone marrow changes, fatty transformation, osteitis, hematopoietic marrow regeneration, osteolysis of symphysis pubis or sacroiliac joints, avascular necrosis, insufficiency fractures, osteoradionecrosis, and radiation-induced neoplasms. Recent Findings: The various radiotherapy effects can be studied and diagnosed by analyzing MR signal intensity, CT attenuation, and FDG-PET activity. Summary: In this review, we report a complete analysis of side effects of radiotherapy on bones, focusing on the spine, chest wall, and pelvis.
| Original language | English |
|---|---|
| Article number | 21 |
| Journal | Current Radiology Reports |
| Volume | 6 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 1 2018 |
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Keywords
- Bones
- Imaging
- Insufficiency fractures
- Radiotherapy (RT)
- Side effects
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Insufficiency Fractures After Radiation Therapy : An Update. / Fusco, Vincenzo; Caivano, Rocchina; Parisi, Salvatore; Troiano, Michele; Corsa, Pietro; Raguso, Arcangela; Munafò, Tindara; Clemente, Maria Antonietta; Guglielmi, Giuseppe.
In: Current Radiology Reports, Vol. 6, No. 7, 21, 01.07.2018.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Insufficiency Fractures After Radiation Therapy
T2 - An Update
AU - Fusco, Vincenzo
AU - Caivano, Rocchina
AU - Parisi, Salvatore
AU - Troiano, Michele
AU - Corsa, Pietro
AU - Raguso, Arcangela
AU - Munafò, Tindara
AU - Clemente, Maria Antonietta
AU - Guglielmi, Giuseppe
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Purpose of Review: Radio therapy, alone or in combination with surgery and/or chemotherapy, is commonly used to treat a variety of neoplasms, resulting in effective local tumor control. Unfortunately radiation therapy can also change the structure of the skeletal system, leading to edema, vascular congestion, areas of hemorrhage, loss of cellularity, focal bone marrow changes, fatty transformation, osteitis, hematopoietic marrow regeneration, osteolysis of symphysis pubis or sacroiliac joints, avascular necrosis, insufficiency fractures, osteoradionecrosis, and radiation-induced neoplasms. Recent Findings: The various radiotherapy effects can be studied and diagnosed by analyzing MR signal intensity, CT attenuation, and FDG-PET activity. Summary: In this review, we report a complete analysis of side effects of radiotherapy on bones, focusing on the spine, chest wall, and pelvis.
AB - Purpose of Review: Radio therapy, alone or in combination with surgery and/or chemotherapy, is commonly used to treat a variety of neoplasms, resulting in effective local tumor control. Unfortunately radiation therapy can also change the structure of the skeletal system, leading to edema, vascular congestion, areas of hemorrhage, loss of cellularity, focal bone marrow changes, fatty transformation, osteitis, hematopoietic marrow regeneration, osteolysis of symphysis pubis or sacroiliac joints, avascular necrosis, insufficiency fractures, osteoradionecrosis, and radiation-induced neoplasms. Recent Findings: The various radiotherapy effects can be studied and diagnosed by analyzing MR signal intensity, CT attenuation, and FDG-PET activity. Summary: In this review, we report a complete analysis of side effects of radiotherapy on bones, focusing on the spine, chest wall, and pelvis.
KW - Bones
KW - Imaging
KW - Insufficiency fractures
KW - Radiotherapy (RT)
KW - Side effects
UR - http://www.scopus.com/inward/record.url?scp=85061691068&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85061691068&partnerID=8YFLogxK
U2 - 10.1007/s40134-018-0280-x
DO - 10.1007/s40134-018-0280-x
M3 - Review article
VL - 6
JO - Current Radiology Reports
JF - Current Radiology Reports
SN - 2167-4825
IS - 7
M1 - 21
ER -