Insulin-like growth factor-II: New roles for an old actor

Stefano Cianfarani

doi:10.3389/fendo.2012.00118

Insulin-like growth factor-II: New roles for an old actor

Stefano Cianfarani

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

Insulin-like growth factor-II (IGF-II), traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator. The aim of this overview is to provide the available evidence, obtained in both experimen- tal conditions and in humans, for a role of IGF-II in the fine-tuning of metabolism and body composition. The underlying mechanisms and the potential clinical implications are discussed.

Original language	English
Article number	Article 118
Journal	Frontiers in Endocrinology
Volume	3
Issue number	OCT
DOIs	https://doi.org/10.3389/fendo.2012.00118
Publication status	Published - 2012

Keywords

Body composition
Insulin
Insulin receptor
Insulin-like growth factor I
Insulin-like growth factor II

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism

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