Insulin pump therapy management in very young children with type 1 diabetes using continuous subcutaneous insulin infusion

Ivana Rabbone, Andrea Scaramuzza, Adriana Bobbio, Riccardo Bonfanti, Dario Iafusco, Fortunato Lombardo, Sonia Toni, Stefano Tumini, Franco Cerutti

Research output: Contribution to journalArticle

Abstract

Background: Compared to older children and adolescents very young patients with type 1 diabetes represent a unique population. We analyzed the age-dependent characteristics and parameters of continuous subcutaneous insulin infusion (CSII) in children under 6 years of age with type 1 diabetes. Methods: We evaluated metabolic control and pump-dependent characteristics in 46 children with type 1 diabetes after 0.89 ± 0.62 years of CSII. Results: Metabolic control significantly improved after CSII initiation (glycosylated hemoglobin, 8.12 ± 1.24% vs. 7.30 ± 0.67%; P <0.05), without increased risk for diabetic ketoacidosis or hypoglycemia. Interestingly, very young patients required bigger boluses than expected, especially in the morning and at the afternoon snack. Conclusions: These data support the need to personalize pump-dependent characteristics, especially in very young children with type 1 diabetes, in order to optimize CSII therapy in this unique age group of patients.

Original languageEnglish
Pages (from-to)707-709
Number of pages3
JournalDiabetes Technology and Therapeutics
Volume11
Issue number11
DOIs
Publication statusPublished - Nov 1 2009

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Subcutaneous Infusions
Type 1 Diabetes Mellitus
Insulin
Diabetic Ketoacidosis
Snacks
Membrane Transport Proteins
Glycosylated Hemoglobin A
Therapeutics
Hypoglycemia
Age Groups
Population

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Medical Laboratory Technology

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Insulin pump therapy management in very young children with type 1 diabetes using continuous subcutaneous insulin infusion. / Rabbone, Ivana; Scaramuzza, Andrea; Bobbio, Adriana; Bonfanti, Riccardo; Iafusco, Dario; Lombardo, Fortunato; Toni, Sonia; Tumini, Stefano; Cerutti, Franco.

In: Diabetes Technology and Therapeutics, Vol. 11, No. 11, 01.11.2009, p. 707-709.

Research output: Contribution to journalArticle

Rabbone, Ivana ; Scaramuzza, Andrea ; Bobbio, Adriana ; Bonfanti, Riccardo ; Iafusco, Dario ; Lombardo, Fortunato ; Toni, Sonia ; Tumini, Stefano ; Cerutti, Franco. / Insulin pump therapy management in very young children with type 1 diabetes using continuous subcutaneous insulin infusion. In: Diabetes Technology and Therapeutics. 2009 ; Vol. 11, No. 11. pp. 707-709.
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AU - Iafusco, Dario

AU - Lombardo, Fortunato

AU - Toni, Sonia

AU - Tumini, Stefano

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