Insulin secretion in migraine: influence on the blood levels of tryptophan.

M. Poloni, G. Nappi, G. Bono, C. Roggi, M. Arpesella, P. Virgilio

Research output: Contribution to journalArticlepeer-review


The blood levels of free tryptophan, glucose and insulin were determined in different groups of patients suffering from headache, initially and after a glucose tolerance and a tolbutamide tolerance test. The control group consisted of subjects without neurological or psychiatric disturbance. A sharp drop of blood tryptophan levels was observed in migraine patients during the tolbutamide tolerance. Migraine attacks may be induced in certain subjects by a disturbance of 5-hydroxytryptamine turnover.

Original languageEnglish
Pages (from-to)67-70
Number of pages4
JournalMonographs in neural sciences
Publication statusPublished - 1976

ASJC Scopus subject areas

  • Medicine(all)


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