IntAct: An open source molecular interaction database

Henning Hermjakob, Luisa Montecchi-Palazzi, Chris Lewington, Sugath Mudali, Samuel Kerrien, Sandra Orchard, Martin Vingron, Bernd Roechert, Peter Roepstorff, Alfonso Valencia, Hanah Margalit, John Armstrong, Amos Bairoch, Gianni Cesareni, David Sherman, Rolf Apweiler

Research output: Contribution to journalArticlepeer-review

Abstract

IntAct provides an open source database and toolkit for the storage, presentation and analysis of protein interactions. The web interface provides both textual and graphical representations of protein interactions, and allows exploring interaction networks in the context of the GO annotations of the interacting proteins. A web service allows direct computational access to retrieve interaction networks in XML format. IntAct currently contains ∼2200 binary and complex interactions imported from the literature and curated in collaboration with the Swiss-Prot team, making intensive use of controlled vocabularies to ensure data consistency. All IntAct software, data and controlled vocabularies are available at http://www.ebi.ac.uk/intact.

Original languageEnglish
JournalNucleic Acids Research
Volume32
Issue numberDATABASE ISS.
Publication statusPublished - Jan 1 2004

ASJC Scopus subject areas

  • Genetics

Fingerprint Dive into the research topics of 'IntAct: An open source molecular interaction database'. Together they form a unique fingerprint.

Cite this