Integrated analysis of myocardial blush and ST-segment elevation recovery after successful primary angioplasty: Real-time grading of microvascular reperfusion and prediction of early and late recovery of left ventricular function

Arnaldo Poli, Raffaela Fetiveau, Pietro Vandoni, Gianfranco Del Rosso, Maurizio D'Urbano, Giovanni Seveso, Francesco Cafiero, Stefano De Servi

Research output: Contribution to journalArticle

Abstract

Background - ST-segment elevation (ΣSTe) recovery and the angiographic myocardial blush (MB) grade are useful markers of microvascular reperfusion after recanalization of the infarct-related artery. We investigated the ability of a combined analysis of MB grade and ΣSTe changes to identify different patterns of myocardial reperfusion shortly after primary percutaneous coronary angioplasty (PTCA) and to predict 7-day and 6-month left ventricular (LV) functional recovery. Methods and Results - MB grade and ΣSTe recovery were evaluated shortly after successful primary PTCA (restoration of TIMI grade 3 flow) in 114 consecutive patients with ΣSTe acute myocardial infarction. LV function was assessed by 2D echocardiograms before PTCA and at 7 days and 6 months thereafter. By combining MB and ΣSTe changes, 3 main groups of patients were identified. Group 1 patients (n=60) had both significant MB (grade 2 to 3) and ΣSTe recovery (

Original languageEnglish
Pages (from-to)313-318
Number of pages6
JournalCirculation
Volume106
Issue number3
DOIs
Publication statusPublished - Jul 16 2002

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Keywords

  • Imaging
  • Myocardial infarction, acute
  • Reperfusion

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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