Integrated care of muscular dystrophies in Italy. Part 1. Pharmacological treatment and rehabilitative interventions

L. Politano, M. Scutifero, M. Patalano, A. Sagliocchi, A. Zaccaro, F. Civati, E. Brighina, G. Vita, S. Messina, M. Sframeli, M.E. Lombardo, R. Scalise, G. Colia, M. Catteruccia, A. Berardinelli, M.C. Motta, A. Gaiani, C. Semplicini, L. Bello, G. AstreaG. Ricci, M.G. D'Angelo, Giuseppe Vita, M. Pane, A. D'Amico, U. Balottin, C. Angelini, R. Battini, L. Magliano

Research output: Contribution to journalArticle

Abstract

This paper describes the pharmacological therapies and rehabilitative interventions received by 502 patients with Muscular Dystrophies, evaluated in relation to patient's socio-demographic and clinical variables, and geographical areas. Data were collected by the MD-Socio-Demographic and Clinical Schedule (MD-SC-CS) and by the Family Problems Questionnaire (FPQ). The most part of the enrolled patients were in drug treatment. The number of the medications increased in relation to patient's age, disability degree and duration of illness and was higher among patients with Duchenne Muscular Dystrophy (DMD) compared with Becker (BMD) or Limb-Girdle Muscular Dystrophies (LGMD). Steroids (deflazacort or prednisone) were the drug most frequently used, followed by cardiologic and bone metabolism drugs. In general, patients using steroids were younger and had a shorter duration of illness; patients using cardiac drugs and dietary supplements were older and had a longer duration of illness. Rehabilitative interventions were provided to about 70% (351/502) of patients, mainly DMD. Of these, physiotherapy was the more frequent treatment (96.6%) and was prevalently performed in rehabilitative centres (about 70% of patients) and at home in only 30%. Hydrokinetic-therapy was practiced by 6.8% of patients. Respiratory rehabilitation was provided to 47.0% of patients (165/351) and assisted mechanical ventilaventilation to 13.1% (46). The amount of rehabilitative interventions increased in relation to the patient's age, level of disability and duration of illness. Compared to Central and Northern Italy, in Southern Italy there was a higher attention to cardiological impairment as shown by a higher number of patients receiving heart drugs. No statistically significant differences concerning the possibility to have access to rehabilitative interventions were noted among the three geographical areas. However, patient living in Southern Italy tend to receive rehabilitation more often at home.
Original languageEnglish
Pages (from-to)19-24
Number of pages6
JournalActa Myologica
Volume36
Issue number1
Publication statusPublished - 2017

Fingerprint

Muscular Dystrophies
Italy
Pharmacology
Therapeutics
Pharmaceutical Preparations
Duchenne Muscular Dystrophy
Rehabilitation
Steroids
Demography
Limb-Girdle Muscular Dystrophies
Dietary Supplements
Prednisone
Appointments and Schedules

Cite this

Politano, L., Scutifero, M., Patalano, M., Sagliocchi, A., Zaccaro, A., Civati, F., ... Magliano, L. (2017). Integrated care of muscular dystrophies in Italy. Part 1. Pharmacological treatment and rehabilitative interventions. Acta Myologica, 36(1), 19-24.

Integrated care of muscular dystrophies in Italy. Part 1. Pharmacological treatment and rehabilitative interventions. / Politano, L.; Scutifero, M.; Patalano, M.; Sagliocchi, A.; Zaccaro, A.; Civati, F.; Brighina, E.; Vita, G.; Messina, S.; Sframeli, M.; Lombardo, M.E.; Scalise, R.; Colia, G.; Catteruccia, M.; Berardinelli, A.; Motta, M.C.; Gaiani, A.; Semplicini, C.; Bello, L.; Astrea, G.; Ricci, G.; D'Angelo, M.G.; Vita, Giuseppe; Pane, M.; D'Amico, A.; Balottin, U.; Angelini, C.; Battini, R.; Magliano, L.

In: Acta Myologica, Vol. 36, No. 1, 2017, p. 19-24.

Research output: Contribution to journalArticle

Politano, L, Scutifero, M, Patalano, M, Sagliocchi, A, Zaccaro, A, Civati, F, Brighina, E, Vita, G, Messina, S, Sframeli, M, Lombardo, ME, Scalise, R, Colia, G, Catteruccia, M, Berardinelli, A, Motta, MC, Gaiani, A, Semplicini, C, Bello, L, Astrea, G, Ricci, G, D'Angelo, MG, Vita, G, Pane, M, D'Amico, A, Balottin, U, Angelini, C, Battini, R & Magliano, L 2017, 'Integrated care of muscular dystrophies in Italy. Part 1. Pharmacological treatment and rehabilitative interventions', Acta Myologica, vol. 36, no. 1, pp. 19-24.
Politano L, Scutifero M, Patalano M, Sagliocchi A, Zaccaro A, Civati F et al. Integrated care of muscular dystrophies in Italy. Part 1. Pharmacological treatment and rehabilitative interventions. Acta Myologica. 2017;36(1):19-24.
Politano, L. ; Scutifero, M. ; Patalano, M. ; Sagliocchi, A. ; Zaccaro, A. ; Civati, F. ; Brighina, E. ; Vita, G. ; Messina, S. ; Sframeli, M. ; Lombardo, M.E. ; Scalise, R. ; Colia, G. ; Catteruccia, M. ; Berardinelli, A. ; Motta, M.C. ; Gaiani, A. ; Semplicini, C. ; Bello, L. ; Astrea, G. ; Ricci, G. ; D'Angelo, M.G. ; Vita, Giuseppe ; Pane, M. ; D'Amico, A. ; Balottin, U. ; Angelini, C. ; Battini, R. ; Magliano, L. / Integrated care of muscular dystrophies in Italy. Part 1. Pharmacological treatment and rehabilitative interventions. In: Acta Myologica. 2017 ; Vol. 36, No. 1. pp. 19-24.
@article{fc2c87d7b19b42ab839531e3412a8055,
title = "Integrated care of muscular dystrophies in Italy. Part 1. Pharmacological treatment and rehabilitative interventions",
abstract = "This paper describes the pharmacological therapies and rehabilitative interventions received by 502 patients with Muscular Dystrophies, evaluated in relation to patient's socio-demographic and clinical variables, and geographical areas. Data were collected by the MD-Socio-Demographic and Clinical Schedule (MD-SC-CS) and by the Family Problems Questionnaire (FPQ). The most part of the enrolled patients were in drug treatment. The number of the medications increased in relation to patient's age, disability degree and duration of illness and was higher among patients with Duchenne Muscular Dystrophy (DMD) compared with Becker (BMD) or Limb-Girdle Muscular Dystrophies (LGMD). Steroids (deflazacort or prednisone) were the drug most frequently used, followed by cardiologic and bone metabolism drugs. In general, patients using steroids were younger and had a shorter duration of illness; patients using cardiac drugs and dietary supplements were older and had a longer duration of illness. Rehabilitative interventions were provided to about 70{\%} (351/502) of patients, mainly DMD. Of these, physiotherapy was the more frequent treatment (96.6{\%}) and was prevalently performed in rehabilitative centres (about 70{\%} of patients) and at home in only 30{\%}. Hydrokinetic-therapy was practiced by 6.8{\%} of patients. Respiratory rehabilitation was provided to 47.0{\%} of patients (165/351) and assisted mechanical ventilaventilation to 13.1{\%} (46). The amount of rehabilitative interventions increased in relation to the patient's age, level of disability and duration of illness. Compared to Central and Northern Italy, in Southern Italy there was a higher attention to cardiological impairment as shown by a higher number of patients receiving heart drugs. No statistically significant differences concerning the possibility to have access to rehabilitative interventions were noted among the three geographical areas. However, patient living in Southern Italy tend to receive rehabilitation more often at home.",
author = "L. Politano and M. Scutifero and M. Patalano and A. Sagliocchi and A. Zaccaro and F. Civati and E. Brighina and G. Vita and S. Messina and M. Sframeli and M.E. Lombardo and R. Scalise and G. Colia and M. Catteruccia and A. Berardinelli and M.C. Motta and A. Gaiani and C. Semplicini and L. Bello and G. Astrea and G. Ricci and M.G. D'Angelo and Giuseppe Vita and M. Pane and A. D'Amico and U. Balottin and C. Angelini and R. Battini and L. Magliano",
note = "Cited By :1 Export Date: 1 March 2018",
year = "2017",
language = "English",
volume = "36",
pages = "19--24",
journal = "Acta Myologica",
issn = "1128-2460",
publisher = "Gaetano Conte Academy",
number = "1",

}

TY - JOUR

T1 - Integrated care of muscular dystrophies in Italy. Part 1. Pharmacological treatment and rehabilitative interventions

AU - Politano, L.

AU - Scutifero, M.

AU - Patalano, M.

AU - Sagliocchi, A.

AU - Zaccaro, A.

AU - Civati, F.

AU - Brighina, E.

AU - Vita, G.

AU - Messina, S.

AU - Sframeli, M.

AU - Lombardo, M.E.

AU - Scalise, R.

AU - Colia, G.

AU - Catteruccia, M.

AU - Berardinelli, A.

AU - Motta, M.C.

AU - Gaiani, A.

AU - Semplicini, C.

AU - Bello, L.

AU - Astrea, G.

AU - Ricci, G.

AU - D'Angelo, M.G.

AU - Vita, Giuseppe

AU - Pane, M.

AU - D'Amico, A.

AU - Balottin, U.

AU - Angelini, C.

AU - Battini, R.

AU - Magliano, L.

N1 - Cited By :1 Export Date: 1 March 2018

PY - 2017

Y1 - 2017

N2 - This paper describes the pharmacological therapies and rehabilitative interventions received by 502 patients with Muscular Dystrophies, evaluated in relation to patient's socio-demographic and clinical variables, and geographical areas. Data were collected by the MD-Socio-Demographic and Clinical Schedule (MD-SC-CS) and by the Family Problems Questionnaire (FPQ). The most part of the enrolled patients were in drug treatment. The number of the medications increased in relation to patient's age, disability degree and duration of illness and was higher among patients with Duchenne Muscular Dystrophy (DMD) compared with Becker (BMD) or Limb-Girdle Muscular Dystrophies (LGMD). Steroids (deflazacort or prednisone) were the drug most frequently used, followed by cardiologic and bone metabolism drugs. In general, patients using steroids were younger and had a shorter duration of illness; patients using cardiac drugs and dietary supplements were older and had a longer duration of illness. Rehabilitative interventions were provided to about 70% (351/502) of patients, mainly DMD. Of these, physiotherapy was the more frequent treatment (96.6%) and was prevalently performed in rehabilitative centres (about 70% of patients) and at home in only 30%. Hydrokinetic-therapy was practiced by 6.8% of patients. Respiratory rehabilitation was provided to 47.0% of patients (165/351) and assisted mechanical ventilaventilation to 13.1% (46). The amount of rehabilitative interventions increased in relation to the patient's age, level of disability and duration of illness. Compared to Central and Northern Italy, in Southern Italy there was a higher attention to cardiological impairment as shown by a higher number of patients receiving heart drugs. No statistically significant differences concerning the possibility to have access to rehabilitative interventions were noted among the three geographical areas. However, patient living in Southern Italy tend to receive rehabilitation more often at home.

AB - This paper describes the pharmacological therapies and rehabilitative interventions received by 502 patients with Muscular Dystrophies, evaluated in relation to patient's socio-demographic and clinical variables, and geographical areas. Data were collected by the MD-Socio-Demographic and Clinical Schedule (MD-SC-CS) and by the Family Problems Questionnaire (FPQ). The most part of the enrolled patients were in drug treatment. The number of the medications increased in relation to patient's age, disability degree and duration of illness and was higher among patients with Duchenne Muscular Dystrophy (DMD) compared with Becker (BMD) or Limb-Girdle Muscular Dystrophies (LGMD). Steroids (deflazacort or prednisone) were the drug most frequently used, followed by cardiologic and bone metabolism drugs. In general, patients using steroids were younger and had a shorter duration of illness; patients using cardiac drugs and dietary supplements were older and had a longer duration of illness. Rehabilitative interventions were provided to about 70% (351/502) of patients, mainly DMD. Of these, physiotherapy was the more frequent treatment (96.6%) and was prevalently performed in rehabilitative centres (about 70% of patients) and at home in only 30%. Hydrokinetic-therapy was practiced by 6.8% of patients. Respiratory rehabilitation was provided to 47.0% of patients (165/351) and assisted mechanical ventilaventilation to 13.1% (46). The amount of rehabilitative interventions increased in relation to the patient's age, level of disability and duration of illness. Compared to Central and Northern Italy, in Southern Italy there was a higher attention to cardiological impairment as shown by a higher number of patients receiving heart drugs. No statistically significant differences concerning the possibility to have access to rehabilitative interventions were noted among the three geographical areas. However, patient living in Southern Italy tend to receive rehabilitation more often at home.

M3 - Article

VL - 36

SP - 19

EP - 24

JO - Acta Myologica

JF - Acta Myologica

SN - 1128-2460

IS - 1

ER -