Integrated cognitive remediation and standard rehabilitation therapy in patients of schizophrenia: persistence after 5 years

M Buonocore, M Spangaro, Margherita Bechi, MA Baraldi, F Cocchi, C Guglielmino, L Bianchi, AR Mastromatteo, M Bosia, R Cavallaro

Research output: Contribution to journalArticle

Abstract

Cognitive remediation, often used in combination with standard rehabilitation programs, represents the best available tool to treat cognitive impairments in patients with schizophrenia. However, there are still open questions about durability of effects and generalization of cognitive improvements to functional outcome. This study aims to investigate the persistence of both cognitive and functional effects of combined cognitive remediation plus standard rehabilitation interventions, 5years after completion of the intervention, also comparing different durations of the standard rehabilitation. Sixty patients diagnosed with schizophrenia and previously treated with a 6months intervention, consisting of standard rehabilitation plus 3-months of cognitive remediation, either followed by another year of standard rehabilitation or routine psychiatric treatment, were reassessed with neuropsychological and functional measures 5years after the intervention. Results show that cognitive abilities remained stable after 5years in both groups, while functional performance significantly decreased in patients treated with the 6months intervention only. Data thus suggest that cognitive effects persist even after 5years, while a longer standard rehabilitation following the cognitive remediation program may be needed to achieve a stable functional gain. Copyright © 2017 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)335-339
Number of pages5
JournalSchizophrenia Research
Volume192
Issue number3
DOIs
Publication statusPublished - 2018

Fingerprint

Schizophrenia
Rehabilitation
Therapeutics
Aptitude
Psychiatry
Cognitive Remediation

Cite this

Integrated cognitive remediation and standard rehabilitation therapy in patients of schizophrenia: persistence after 5 years. / Buonocore, M; Spangaro, M; Bechi, Margherita; Baraldi, MA; Cocchi, F; Guglielmino, C; Bianchi, L; Mastromatteo, AR; Bosia, M; Cavallaro, R.

In: Schizophrenia Research, Vol. 192, No. 3, 2018, p. 335-339.

Research output: Contribution to journalArticle

Buonocore, M, Spangaro, M, Bechi, M, Baraldi, MA, Cocchi, F, Guglielmino, C, Bianchi, L, Mastromatteo, AR, Bosia, M & Cavallaro, R 2018, 'Integrated cognitive remediation and standard rehabilitation therapy in patients of schizophrenia: persistence after 5 years', Schizophrenia Research, vol. 192, no. 3, pp. 335-339. https://doi.org/10.1016/j.schres.2017.05.022
Buonocore, M ; Spangaro, M ; Bechi, Margherita ; Baraldi, MA ; Cocchi, F ; Guglielmino, C ; Bianchi, L ; Mastromatteo, AR ; Bosia, M ; Cavallaro, R. / Integrated cognitive remediation and standard rehabilitation therapy in patients of schizophrenia: persistence after 5 years. In: Schizophrenia Research. 2018 ; Vol. 192, No. 3. pp. 335-339.
@article{c3381de69f214d52bbe416cd75e6feba,
title = "Integrated cognitive remediation and standard rehabilitation therapy in patients of schizophrenia: persistence after 5 years",
abstract = "Cognitive remediation, often used in combination with standard rehabilitation programs, represents the best available tool to treat cognitive impairments in patients with schizophrenia. However, there are still open questions about durability of effects and generalization of cognitive improvements to functional outcome. This study aims to investigate the persistence of both cognitive and functional effects of combined cognitive remediation plus standard rehabilitation interventions, 5years after completion of the intervention, also comparing different durations of the standard rehabilitation. Sixty patients diagnosed with schizophrenia and previously treated with a 6months intervention, consisting of standard rehabilitation plus 3-months of cognitive remediation, either followed by another year of standard rehabilitation or routine psychiatric treatment, were reassessed with neuropsychological and functional measures 5years after the intervention. Results show that cognitive abilities remained stable after 5years in both groups, while functional performance significantly decreased in patients treated with the 6months intervention only. Data thus suggest that cognitive effects persist even after 5years, while a longer standard rehabilitation following the cognitive remediation program may be needed to achieve a stable functional gain. Copyright {\circledC} 2017 Elsevier B.V. All rights reserved.",
author = "M Buonocore and M Spangaro and Margherita Bechi and MA Baraldi and F Cocchi and C Guglielmino and L Bianchi and AR Mastromatteo and M Bosia and R Cavallaro",
year = "2018",
doi = "10.1016/j.schres.2017.05.022",
language = "English",
volume = "192",
pages = "335--339",
journal = "Schizophrenia Research",
issn = "0920-9964",
publisher = "Elsevier B.V.",
number = "3",

}

TY - JOUR

T1 - Integrated cognitive remediation and standard rehabilitation therapy in patients of schizophrenia: persistence after 5 years

AU - Buonocore, M

AU - Spangaro, M

AU - Bechi, Margherita

AU - Baraldi, MA

AU - Cocchi, F

AU - Guglielmino, C

AU - Bianchi, L

AU - Mastromatteo, AR

AU - Bosia, M

AU - Cavallaro, R

PY - 2018

Y1 - 2018

N2 - Cognitive remediation, often used in combination with standard rehabilitation programs, represents the best available tool to treat cognitive impairments in patients with schizophrenia. However, there are still open questions about durability of effects and generalization of cognitive improvements to functional outcome. This study aims to investigate the persistence of both cognitive and functional effects of combined cognitive remediation plus standard rehabilitation interventions, 5years after completion of the intervention, also comparing different durations of the standard rehabilitation. Sixty patients diagnosed with schizophrenia and previously treated with a 6months intervention, consisting of standard rehabilitation plus 3-months of cognitive remediation, either followed by another year of standard rehabilitation or routine psychiatric treatment, were reassessed with neuropsychological and functional measures 5years after the intervention. Results show that cognitive abilities remained stable after 5years in both groups, while functional performance significantly decreased in patients treated with the 6months intervention only. Data thus suggest that cognitive effects persist even after 5years, while a longer standard rehabilitation following the cognitive remediation program may be needed to achieve a stable functional gain. Copyright © 2017 Elsevier B.V. All rights reserved.

AB - Cognitive remediation, often used in combination with standard rehabilitation programs, represents the best available tool to treat cognitive impairments in patients with schizophrenia. However, there are still open questions about durability of effects and generalization of cognitive improvements to functional outcome. This study aims to investigate the persistence of both cognitive and functional effects of combined cognitive remediation plus standard rehabilitation interventions, 5years after completion of the intervention, also comparing different durations of the standard rehabilitation. Sixty patients diagnosed with schizophrenia and previously treated with a 6months intervention, consisting of standard rehabilitation plus 3-months of cognitive remediation, either followed by another year of standard rehabilitation or routine psychiatric treatment, were reassessed with neuropsychological and functional measures 5years after the intervention. Results show that cognitive abilities remained stable after 5years in both groups, while functional performance significantly decreased in patients treated with the 6months intervention only. Data thus suggest that cognitive effects persist even after 5years, while a longer standard rehabilitation following the cognitive remediation program may be needed to achieve a stable functional gain. Copyright © 2017 Elsevier B.V. All rights reserved.

U2 - 10.1016/j.schres.2017.05.022

DO - 10.1016/j.schres.2017.05.022

M3 - Article

VL - 192

SP - 335

EP - 339

JO - Schizophrenia Research

JF - Schizophrenia Research

SN - 0920-9964

IS - 3

ER -