Integrated treatment in locally advanced carcinoma of the oropharynx

Laura Lanza, Lucio Rizzi, Domenico Durso, Antonio Occhini, Marco Benazzo, Carmine Tinelli

Research output: Contribution to journalArticle

Abstract

Background and Objectives: Oropharyngeal carcinoma tends to be aggressive and deeply infiltrative of nearby sites, with an high incidence of lymphnode metastases. The last treatment decision generally depends on the stage of the lesion and the patient's general status. Oropharyngeal tumor is generally treated by integrated treatments. Methods: We retrospectively studied 115 patients with locally advanced oropharyngeal tumors treated in our institution with combined therapies compare the results in two differents groups of patients (surgery plus radiotherapy and chemotherapy plus radiotherapy). Results: The 3-year overall survival rate in patients who underwent surgery plus radiotherapy was 82% and in those who underwent chemotherapy plus radiotherapy was 49%. Conclusion: The results suggest that surgery followed by radiotherapy seems to be the best treatment in the case of locally advanced oropharyngeal tumor. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish
Pages (from-to)75-78
Number of pages4
JournalJournal of Surgical Oncology
Volume74
Issue number1
DOIs
Publication statusPublished - 2000

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Oropharynx
Radiotherapy
Carcinoma
Therapeutics
Drug Therapy
Neoplasms
Survival Rate
Neoplasm Metastasis
Incidence

Keywords

  • Integrated treatment
  • Oropharyngeal cancer

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Integrated treatment in locally advanced carcinoma of the oropharynx. / Lanza, Laura; Rizzi, Lucio; Durso, Domenico; Occhini, Antonio; Benazzo, Marco; Tinelli, Carmine.

In: Journal of Surgical Oncology, Vol. 74, No. 1, 2000, p. 75-78.

Research output: Contribution to journalArticle

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AU - Durso, Domenico

AU - Occhini, Antonio

AU - Benazzo, Marco

AU - Tinelli, Carmine

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