Integration of CT/PET images for the optimization of radiotherapy planning

G. Rizzo, G. M. Cattaneo, I. Castiglioni, M. Reni, D. Vanni, C. Pasquali, C. Landoni, M. C. Gilardi, S. Cerutti, F. Fazio

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A procedure is presented, based on the combined use of two different tomographic imaging modalities (PET and CT), aimed at the optimization of radiotherapy planning. The combined use of functional PET and anatomical CT studies allows a better definition of the tumour mass with respect to the conventional CT based approach. The proposed procedure consists in: a) spatial registration of CT and PET studies; b) contour drawing based on the combined observation of PET and CT. The set of contours thus obtained, defining optimized volumes of interest for radiotherapy, can be exported to the treatment planning system for designing the radiation beams geometry. The accuracy of the image registration was evaluated by phantom studies and found to be less than 2 pixels in plane and less than slice thickness axially, with respect to CT. The application of the procedure to the case of a patient affected by pancreatic tumour is presented, showing how the treatment planning can be improved by multimodal CT/PET information.

Original languageEnglish
Title of host publicationAnnual Reports of the Research Reactor Institute, Kyoto University
Pages2756-2758
Number of pages3
Volume3
Publication statusPublished - 2001
Event23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Istanbul, Turkey
Duration: Oct 25 2001Oct 28 2001

Other

Other23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CountryTurkey
CityIstanbul
Period10/25/0110/28/01

Keywords

  • Multimodal registration
  • PET
  • Radiotherapy

ASJC Scopus subject areas

  • Energy Engineering and Power Technology
  • Mechanical Engineering

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