Integration of new biological and physical retrospective dosimetry methods into EU emergency response plans–joint RENEB and EURADOS inter-laboratory comparisons

Elizabeth Ainsbury, Christophe Badie, Stephen Barnard, Grainne Manning, Jayne Moquet, Michael Abend, Ana Catarina Antunes, Lleonard Barrios, Celine Bassinet, Christina Beinke, Emanuela Bortolin, Lily Bossin, Clare Bricknell, Kamil Brzoska, Iwona Buraczewska, Carlos Huertas Castaño, Zina Čemusová, Maria Christiansson, Santiago Mateos Cordero, Guillaume CoslerSara Della Monaca, François Desangles, Michael Discher, Inmaculada Dominguez, Sven Doucha-Senf, Jon Eakins, Paola Fattibene, Silvia Filippi, Monika Frenzel, Dimka Georgieva, Eric Gregoire, Kamile Guogyte, Valeria Hadjidekova, Ljubomira Hadjiiska, Rositsa Hristova, Maria Karakosta, Enikő Kis, Ralf Kriehuber, Jungil Lee, David Lloyd, Katalin Lumniczky, Fiona Lyng, Ellina Macaeva, Matthaeus Majewski, S. Vanda Martins, Stephen W.S. McKeever, Aidan Meade, Dinesh Medipally, Roberta Meschini, Maria Cristina Quattrini

Research output: Contribution to journalArticle

Abstract

Purpose: RENEB, ‘Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,’ is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely active network, a number of new dosimetry methods have recently been proposed or developed. There is a requirement to test and/or validate these candidate techniques and inter-comparison exercises are a well-established method for such validation. Materials and methods: The authors present details of inter-comparisons of four such new methods: dicentric chromosome analysis including telomere and centromere staining; the gene expression assay carried out in whole blood; Raman spectroscopy on blood lymphocytes, and detection of radiation-induced thermoluminescent signals in glass screens taken from mobile phones. Results: In general the results show good agreement between the laboratories and methods within the expected levels of uncertainty, and thus demonstrate that there is a lot of potential for each of the candidate techniques. Conclusions: Further work is required before the new methods can be included within the suite of reliable dosimetry methods for use by RENEB partners and others in routine and emergency response scenarios.

Original languageEnglish
Pages (from-to)99-109
Number of pages11
JournalInternational Journal of Radiation Biology
Volume93
Issue number1
DOIs
Publication statusPublished - Jan 2 2017

Keywords

  • Biodosimetry
  • physical retrospective dosimetry
  • radiation accidents
  • RENEB

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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    Ainsbury, E., Badie, C., Barnard, S., Manning, G., Moquet, J., Abend, M., Antunes, A. C., Barrios, L., Bassinet, C., Beinke, C., Bortolin, E., Bossin, L., Bricknell, C., Brzoska, K., Buraczewska, I., Castaño, C. H., Čemusová, Z., Christiansson, M., Cordero, S. M., ... Quattrini, M. C. (2017). Integration of new biological and physical retrospective dosimetry methods into EU emergency response plans–joint RENEB and EURADOS inter-laboratory comparisons. International Journal of Radiation Biology, 93(1), 99-109. https://doi.org/10.1080/09553002.2016.1206233