Integrin expression and adhesion property of osteoclast-like cells from giant cell tumours of bone.

M. Grano, S. Colucci, P. Zigrino, M. Serra, K. Scotlandi, A. Teti, A. Zambonin Zallone

Research output: Contribution to journalArticle

Abstract

Cells cultured from human giant cell tumours of bone were used to study interactions with different extracellular matrix proteins as Collagen, Fibronectin, Osteocalcin, Thrombospondin and Bone Sialoprotein II. Cells were capable of recognizing these substrata; beta 3 integrin subunit was distributed in focal adhesions, together with beta 1 on BSPII, FN, and in presence of serum, whereas and presented a diffuse organization onto the other substrate. beta 1 alone was expressed over collagen coated coverslips.

Original languageEnglish
Pages (from-to)255-258
Number of pages4
JournalBollettino della Societa Italiana di Biologia Sperimentale
Volume68
Issue number4
Publication statusPublished - Apr 1992

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Giant Cell Tumor of Bone
Osteoclasts
Integrins
Collagen
Integrin-Binding Sialoprotein
Integrin beta3
Thrombospondins
Focal Adhesions
Extracellular Matrix Proteins
Osteocalcin
Fibronectins
Cultured Cells
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Integrin expression and adhesion property of osteoclast-like cells from giant cell tumours of bone. / Grano, M.; Colucci, S.; Zigrino, P.; Serra, M.; Scotlandi, K.; Teti, A.; Zambonin Zallone, A.

In: Bollettino della Societa Italiana di Biologia Sperimentale, Vol. 68, No. 4, 04.1992, p. 255-258.

Research output: Contribution to journalArticle

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