Abstract
Neoplastic transformation results in rearrangement of the cell membrane with a breakdown of the regular expression of adhesion molecules such as integrins. A relationship may exist between the intensity of this alteration, and the form it takes, and a tumour's ability to metastatise. We studied this possibility by investigating the epithelial integrin expression of 35 head and neck squamous cell carcinomas. Two types of positivity were observed: one associated with tumours with a better prognostic index, the other with those characterized by greater malignancy.
Original language | English |
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Pages (from-to) | 328-330 |
Number of pages | 3 |
Journal | Acta Oto-Laryngologica |
Volume | 115 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1995 |
Keywords
- Adhesion molecules
- Head and neck cancers
- Integrins
ASJC Scopus subject areas
- Otorhinolaryngology