Integrin expression in head and neck cancers

G. Cortesina; M. Sacchi; M. Bussi; B. Panizzut; S. Ferro; M. T. Carlevato; P. C. Marchisio

doi:10.3109/00016489509139322

Integrin expression in head and neck cancers

G. Cortesina, M. Sacchi, M. Bussi, B. Panizzut, S. Ferro, M. T. Carlevato, P. C. Marchisio

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Neoplastic transformation results in rearrangement of the cell membrane with a breakdown of the regular expression of adhesion molecules such as integrins. A relationship may exist between the intensity of this alteration, and the form it takes, and a tumour's ability to metastatise. We studied this possibility by investigating the epithelial integrin expression of 35 head and neck squamous cell carcinomas. Two types of positivity were observed: one associated with tumours with a better prognostic index, the other with those characterized by greater malignancy.

Original language	English
Pages (from-to)	328-330
Number of pages	3
Journal	Acta Oto-Laryngologica
Volume	115
Issue number	2
DOIs	https://doi.org/10.3109/00016489509139322
Publication status	Published - 1995

Keywords

Adhesion molecules
Head and neck cancers
Integrins

ASJC Scopus subject areas

Otorhinolaryngology

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10.3109/00016489509139322

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AU - Cortesina, G.

AU - Sacchi, M.

AU - Bussi, M.

AU - Panizzut, B.

AU - Ferro, S.

AU - Carlevato, M. T.

AU - Marchisio, P. C.

PY - 1995

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AB - Neoplastic transformation results in rearrangement of the cell membrane with a breakdown of the regular expression of adhesion molecules such as integrins. A relationship may exist between the intensity of this alteration, and the form it takes, and a tumour's ability to metastatise. We studied this possibility by investigating the epithelial integrin expression of 35 head and neck squamous cell carcinomas. Two types of positivity were observed: one associated with tumours with a better prognostic index, the other with those characterized by greater malignancy.

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KW - Integrins

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Integrin expression in head and neck cancers

Abstract

Keywords

ASJC Scopus subject areas

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