Abstract
Neoplastic transformation results in rearrangement of the cell membrane with a breakdown of the regular expression of adhesion molecules such as integrins. A relationship may exist between the intensity of this alteration, and the form it takes, and a tumour's ability to metastatise. We studied this possibility by investigating the epithelial integrin expression of 35 head and neck squamous cell carcinomas. Two types of positivity were observed: one associated with tumours with a better prognostic index, the other with those characterized by greater malignancy.
| Original language | English |
|---|---|
| Pages (from-to) | 328-330 |
| Number of pages | 3 |
| Journal | Acta Oto-Laryngologica |
| Volume | 115 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1995 |
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Keywords
- Adhesion molecules
- Head and neck cancers
- Integrins
ASJC Scopus subject areas
- Otorhinolaryngology
Cite this
Integrin expression in head and neck cancers. / Cortesina, G.; Sacchi, M.; Bussi, M.; Panizzut, B.; Ferro, S.; Carlevato, M. T.; Marchisio, P. C.
In: Acta Oto-Laryngologica, Vol. 115, No. 2, 1995, p. 328-330.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Integrin expression in head and neck cancers
AU - Cortesina, G.
AU - Sacchi, M.
AU - Bussi, M.
AU - Panizzut, B.
AU - Ferro, S.
AU - Carlevato, M. T.
AU - Marchisio, P. C.
PY - 1995
Y1 - 1995
N2 - Neoplastic transformation results in rearrangement of the cell membrane with a breakdown of the regular expression of adhesion molecules such as integrins. A relationship may exist between the intensity of this alteration, and the form it takes, and a tumour's ability to metastatise. We studied this possibility by investigating the epithelial integrin expression of 35 head and neck squamous cell carcinomas. Two types of positivity were observed: one associated with tumours with a better prognostic index, the other with those characterized by greater malignancy.
AB - Neoplastic transformation results in rearrangement of the cell membrane with a breakdown of the regular expression of adhesion molecules such as integrins. A relationship may exist between the intensity of this alteration, and the form it takes, and a tumour's ability to metastatise. We studied this possibility by investigating the epithelial integrin expression of 35 head and neck squamous cell carcinomas. Two types of positivity were observed: one associated with tumours with a better prognostic index, the other with those characterized by greater malignancy.
KW - Adhesion molecules
KW - Head and neck cancers
KW - Integrins
UR - http://www.scopus.com/inward/record.url?scp=0028904288&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028904288&partnerID=8YFLogxK
U2 - 10.3109/00016489509139322
DO - 10.3109/00016489509139322
M3 - Article
VL - 115
SP - 328
EP - 330
JO - Acta Oto-Laryngologica
JF - Acta Oto-Laryngologica
SN - 0001-6489
IS - 2
ER -