Integrin expression in head and neck cancers

G. Cortesina, M. Sacchi, M. Bussi, B. Panizzut, S. Ferro, M. T. Carlevato, P. C. Marchisio

Research output: Contribution to journalArticlepeer-review

Abstract

Neoplastic transformation results in rearrangement of the cell membrane with a breakdown of the regular expression of adhesion molecules such as integrins. A relationship may exist between the intensity of this alteration, and the form it takes, and a tumour's ability to metastatise. We studied this possibility by investigating the epithelial integrin expression of 35 head and neck squamous cell carcinomas. Two types of positivity were observed: one associated with tumours with a better prognostic index, the other with those characterized by greater malignancy.

Original languageEnglish
Pages (from-to)328-330
Number of pages3
JournalActa Oto-Laryngologica
Volume115
Issue number2
DOIs
Publication statusPublished - 1995

Keywords

  • Adhesion molecules
  • Head and neck cancers
  • Integrins

ASJC Scopus subject areas

  • Otorhinolaryngology

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