Inteins in mycobacterial GyrA are a taxonomic character

Peter Sander, Fernando Alcaide, Ingeborg Richter, Klaus Frischkorn, Enrico Tortoli, Burkhard Springer, Amalio Telenti, Erik C. Böttger

Research output: Contribution to journalArticlepeer-review

Abstract

The A subunit of DNA gyrase in mycobacteria is frequently subjected to splicing events as its gene, gyrA, harbours an insertion encoding an intein. Investigation of a number of different isolates of Mycobacterium kansasii, Mycobacterium malmoense, Mycobacterium marinum, Mycobacterium ulcerans and Mycobacterium xenopi demonstrated that the presence of GyrA inteins is not random but a taxonomic character specific for a given taxon at a species or subspecies level.

Original languageEnglish
Pages (from-to)589-591
Number of pages3
JournalMicrobiology
Volume144
Issue number2
Publication statusPublished - Feb 1998

Keywords

  • GyrA
  • Intein
  • Mycobacteria
  • Myobacterium kansasii

ASJC Scopus subject areas

  • Microbiology

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