Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretroviral therapy

Joseph Kulkosky, Giuseppe Nunnari, Miguel Otero, Sandra Calarota, Geetha Dornadula, Hui Zhang, Anne Malin, Julie Sullivan, Yan Xu, Joseph DeSimone, Timothy Babinchak, John Stern, Winston Cavert, Ashley Haase, Roger J. Pomerantz

Research output: Contribution to journalArticle

115 Citations (Scopus)

Abstract

Highly active antiretroviral therapy (HAART) has led to significant changes in mortality and morbidity in the human immunodeficiency virus type 1 (HIV-1) epidemic. Nevertheless, because of molecular mechanisms of viral persistence, HAART does not eradicate HIV-1. Didanosine and hydroxyurea were added to the antiretroviral regimens of 3 HIV-1-infected men who were receiving stable HAART and who had HIV-1 RNA levels

Original languageEnglish
Pages (from-to)1403-1411
Number of pages9
JournalJournal of Infectious Diseases
Volume186
Issue number10
DOIs
Publication statusPublished - Nov 15 2002

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Highly Active Antiretroviral Therapy
HIV-1
Didanosine
Hydroxyurea
Therapeutics
RNA
Morbidity
Mortality

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Immunology

Cite this

Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretroviral therapy. / Kulkosky, Joseph; Nunnari, Giuseppe; Otero, Miguel; Calarota, Sandra; Dornadula, Geetha; Zhang, Hui; Malin, Anne; Sullivan, Julie; Xu, Yan; DeSimone, Joseph; Babinchak, Timothy; Stern, John; Cavert, Winston; Haase, Ashley; Pomerantz, Roger J.

In: Journal of Infectious Diseases, Vol. 186, No. 10, 15.11.2002, p. 1403-1411.

Research output: Contribution to journalArticle

Kulkosky, J, Nunnari, G, Otero, M, Calarota, S, Dornadula, G, Zhang, H, Malin, A, Sullivan, J, Xu, Y, DeSimone, J, Babinchak, T, Stern, J, Cavert, W, Haase, A & Pomerantz, RJ 2002, 'Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretroviral therapy', Journal of Infectious Diseases, vol. 186, no. 10, pp. 1403-1411. https://doi.org/10.1086/344357
Kulkosky, Joseph ; Nunnari, Giuseppe ; Otero, Miguel ; Calarota, Sandra ; Dornadula, Geetha ; Zhang, Hui ; Malin, Anne ; Sullivan, Julie ; Xu, Yan ; DeSimone, Joseph ; Babinchak, Timothy ; Stern, John ; Cavert, Winston ; Haase, Ashley ; Pomerantz, Roger J. / Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretroviral therapy. In: Journal of Infectious Diseases. 2002 ; Vol. 186, No. 10. pp. 1403-1411.
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