Intensive care unit admission in children with malignant or nonmalignant disease: Incidence, outcome, and prognostic factors: A single-center experience

Maura Faraci; Francesca Bagnasco; Stefano Giardino; Massimo Conte; Concetta Micalizzi; Elio Castagnola; Elisabetta Lampugnani; Andrea Moscatelli; Alessia Franceschi; Joseph A. Carcillo; Riccardo Haupt

doi:10.1097/MPH.0000000000000048

Intensive care unit admission in children with malignant or nonmalignant disease: Incidence, outcome, and prognostic factors: A single-center experience

Maura Faraci, Francesca Bagnasco, Stefano Giardino, Massimo Conte, Concetta Micalizzi, Elio Castagnola, Elisabetta Lampugnani, Andrea Moscatelli, Alessia Franceschi, Joseph A. Carcillo, Riccardo Haupt

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article

Abstract

OBJECTIVE: To investigate pediatric intensive care unit (PICU) admission in children with malignant and nonmalignant diseases who developed life-threatening complications. PATIENTS AND METHODS: Between 1999 and 2010, of the 1278 eligible pediatric patients treated for a malignant or nonmalignant disease, 54 were admitted to the PICU for respiratory distress (40.7%), neurological events (33.3%), severe sepsis (14.8%), and organ failure (11.2%). RESULTS: Rate of PICU admission was 4.2%, with a 2-year cumulative incidence of 4.5%. Risk factors associated with higher cumulative incidence of PICU admission were older age at study entry (P=0.003), nonmalignant underlying disease (P=0.015), and hematopoietic stem cell transplantation (P

Original language	English
Journal	Journal of Pediatric Hematology/Oncology
DOIs	https://doi.org/10.1097/MPH.0000000000000048
Publication status	Accepted/In press - Oct 31 2013

ASJC Scopus subject areas

Hematology
Oncology
Pediatrics, Perinatology, and Child Health

Access to Document

10.1097/MPH.0000000000000048

Fingerprint Dive into the research topics of 'Intensive care unit admission in children with malignant or nonmalignant disease: Incidence, outcome, and prognostic factors: A single-center experience'. Together they form a unique fingerprint.

Cite this

Faraci, M., Bagnasco, F., Giardino, S., Conte, M., Micalizzi, C., Castagnola, E., Lampugnani, E., Moscatelli, A., Franceschi, A., Carcillo, J. A., & Haupt, R. (Accepted/In press). Intensive care unit admission in children with malignant or nonmalignant disease: Incidence, outcome, and prognostic factors: A single-center experience. Journal of Pediatric Hematology/Oncology. https://doi.org/10.1097/MPH.0000000000000048

Intensive care unit admission in children with malignant or nonmalignant disease : Incidence, outcome, and prognostic factors: A single-center experience. / Faraci, Maura ; Bagnasco, Francesca ; Giardino, Stefano ; Conte, Massimo ; Micalizzi, Concetta ; Castagnola, Elio ; Lampugnani, Elisabetta ; Moscatelli, Andrea; Franceschi, Alessia; Carcillo, Joseph A.; Haupt, Riccardo.

In: Journal of Pediatric Hematology/Oncology, 31.10.2013.

Research output: Contribution to journal › Article

Faraci, M , Bagnasco, F , Giardino, S , Conte, M , Micalizzi, C , Castagnola, E , Lampugnani, E , Moscatelli, A, Franceschi, A, Carcillo, JA & Haupt, R 2013, 'Intensive care unit admission in children with malignant or nonmalignant disease: Incidence, outcome, and prognostic factors: A single-center experience', Journal of Pediatric Hematology/Oncology. https://doi.org/10.1097/MPH.0000000000000048

Faraci, Maura ; Bagnasco, Francesca ; Giardino, Stefano ; Conte, Massimo ; Micalizzi, Concetta ; Castagnola, Elio ; Lampugnani, Elisabetta ; Moscatelli, Andrea ; Franceschi, Alessia ; Carcillo, Joseph A. ; Haupt, Riccardo. / Intensive care unit admission in children with malignant or nonmalignant disease : Incidence, outcome, and prognostic factors: A single-center experience. In: Journal of Pediatric Hematology/Oncology. 2013.

@article{3292f81c4b6548f6b0aa1429bd71b5ac,

title = "Intensive care unit admission in children with malignant or nonmalignant disease: Incidence, outcome, and prognostic factors: A single-center experience",

abstract = "OBJECTIVE: To investigate pediatric intensive care unit (PICU) admission in children with malignant and nonmalignant diseases who developed life-threatening complications. PATIENTS AND METHODS: Between 1999 and 2010, of the 1278 eligible pediatric patients treated for a malignant or nonmalignant disease, 54 were admitted to the PICU for respiratory distress (40.7%), neurological events (33.3%), severe sepsis (14.8%), and organ failure (11.2%). RESULTS: Rate of PICU admission was 4.2%, with a 2-year cumulative incidence of 4.5%. Risk factors associated with higher cumulative incidence of PICU admission were older age at study entry (P=0.003), nonmalignant underlying disease (P=0.015), and hematopoietic stem cell transplantation (P",

author = "Maura Faraci and Francesca Bagnasco and Stefano Giardino and Massimo Conte and Concetta Micalizzi and Elio Castagnola and Elisabetta Lampugnani and Andrea Moscatelli and Alessia Franceschi and Carcillo, {Joseph A.} and Riccardo Haupt",

year = "2013",

month = oct,

day = "31",

doi = "10.1097/MPH.0000000000000048",

language = "English",

journal = "Journal of Pediatric Hematology/Oncology",

issn = "1077-4114",

publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Intensive care unit admission in children with malignant or nonmalignant disease

T2 - Incidence, outcome, and prognostic factors: A single-center experience

AU - Faraci, Maura

AU - Bagnasco, Francesca

AU - Giardino, Stefano

AU - Conte, Massimo

AU - Micalizzi, Concetta

AU - Castagnola, Elio

AU - Lampugnani, Elisabetta

AU - Moscatelli, Andrea

AU - Franceschi, Alessia

AU - Carcillo, Joseph A.

AU - Haupt, Riccardo

PY - 2013/10/31

Y1 - 2013/10/31

N2 - OBJECTIVE: To investigate pediatric intensive care unit (PICU) admission in children with malignant and nonmalignant diseases who developed life-threatening complications. PATIENTS AND METHODS: Between 1999 and 2010, of the 1278 eligible pediatric patients treated for a malignant or nonmalignant disease, 54 were admitted to the PICU for respiratory distress (40.7%), neurological events (33.3%), severe sepsis (14.8%), and organ failure (11.2%). RESULTS: Rate of PICU admission was 4.2%, with a 2-year cumulative incidence of 4.5%. Risk factors associated with higher cumulative incidence of PICU admission were older age at study entry (P=0.003), nonmalignant underlying disease (P=0.015), and hematopoietic stem cell transplantation (P

AB - OBJECTIVE: To investigate pediatric intensive care unit (PICU) admission in children with malignant and nonmalignant diseases who developed life-threatening complications. PATIENTS AND METHODS: Between 1999 and 2010, of the 1278 eligible pediatric patients treated for a malignant or nonmalignant disease, 54 were admitted to the PICU for respiratory distress (40.7%), neurological events (33.3%), severe sepsis (14.8%), and organ failure (11.2%). RESULTS: Rate of PICU admission was 4.2%, with a 2-year cumulative incidence of 4.5%. Risk factors associated with higher cumulative incidence of PICU admission were older age at study entry (P=0.003), nonmalignant underlying disease (P=0.015), and hematopoietic stem cell transplantation (P

UR - http://www.scopus.com/inward/record.url?scp=84886742492&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84886742492&partnerID=8YFLogxK

U2 - 10.1097/MPH.0000000000000048

DO - 10.1097/MPH.0000000000000048

M3 - Article

JO - Journal of Pediatric Hematology/Oncology

JF - Journal of Pediatric Hematology/Oncology

SN - 1077-4114

ER -