TY - JOUR
T1 - Intensive care unit admission in children with malignant or nonmalignant disease
T2 - Incidence, outcome, and prognostic factors: A single-center experience
AU - Faraci, Maura
AU - Bagnasco, Francesca
AU - Giardino, Stefano
AU - Conte, Massimo
AU - Micalizzi, Concetta
AU - Castagnola, Elio
AU - Lampugnani, Elisabetta
AU - Moscatelli, Andrea
AU - Franceschi, Alessia
AU - Carcillo, Joseph A.
AU - Haupt, Riccardo
PY - 2013/10/31
Y1 - 2013/10/31
N2 - OBJECTIVE: To investigate pediatric intensive care unit (PICU) admission in children with malignant and nonmalignant diseases who developed life-threatening complications. PATIENTS AND METHODS: Between 1999 and 2010, of the 1278 eligible pediatric patients treated for a malignant or nonmalignant disease, 54 were admitted to the PICU for respiratory distress (40.7%), neurological events (33.3%), severe sepsis (14.8%), and organ failure (11.2%). RESULTS: Rate of PICU admission was 4.2%, with a 2-year cumulative incidence of 4.5%. Risk factors associated with higher cumulative incidence of PICU admission were older age at study entry (P=0.003), nonmalignant underlying disease (P=0.015), and hematopoietic stem cell transplantation (P
AB - OBJECTIVE: To investigate pediatric intensive care unit (PICU) admission in children with malignant and nonmalignant diseases who developed life-threatening complications. PATIENTS AND METHODS: Between 1999 and 2010, of the 1278 eligible pediatric patients treated for a malignant or nonmalignant disease, 54 were admitted to the PICU for respiratory distress (40.7%), neurological events (33.3%), severe sepsis (14.8%), and organ failure (11.2%). RESULTS: Rate of PICU admission was 4.2%, with a 2-year cumulative incidence of 4.5%. Risk factors associated with higher cumulative incidence of PICU admission were older age at study entry (P=0.003), nonmalignant underlying disease (P=0.015), and hematopoietic stem cell transplantation (P
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U2 - 10.1097/MPH.0000000000000048
DO - 10.1097/MPH.0000000000000048
M3 - Article
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
SN - 1077-4114
ER -