Interaction between respiration and beat-by-beat ventricular parameters from acoustic quantification

E. G. Caiani, M. Turiel, S. Muzzupappa, L. Colombo, A. Gandini, A. Porta, G. Baselli, S. Cerutti

Research output: Chapter in Book/Report/Conference proceedingConference contribution


In 8 patients with cardiac dilative myopathy and pseudo-normalized mitral Doppler pattern (DP, age 60±2, mean±SE), and in 11 age-matched control subjects (NL, age 61±4), beat-by-beat end diastolic (EDV), end systolic (ESV), stroke (SV) ventricular volume (VV) measurements were obtained at rest for periods of at least 4 min by echocardiographic acoustic quantification (AQ) signal. RR intervals and respiration were recorded as well. In all subjects, spectral analysis showed a prevalence of high frequency (HF) component in all VV series, with an increased absolute power in DP (53±12 ml2 of HF SV variability compared to 16±5 in NL). Folded scatter diagrams of the VV values vs. the respiratory phase revealed consistent patterns. Parameters of a linear prediction model of SV were estimated by considering as inputs: 1) three samples of respiration; 2) the previous sample of EDV slow trends; 3) the previous RR interval with a goodness of fit of 47±4% in NL and 43±6% in DP.

Original languageEnglish
Title of host publicationComputers in Cardiology
Number of pages4
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine


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