Abstract
Some of the most invalidating symptoms in subjects with chronic heart failure, such as dyspnea and poor exercise tolerance, correlate poorly with indices of myocardial pump function, but are more related to alterations in autonomic nervous system, respiratory system, in addition to physical deconditioning. Increasing evidence suggests that in addition to pump function abnormalities, sympathetic and parasympathetic abnormalities, increased function of baro-, chemo- and ergoreflex control mechanisms play a pivotal role in the origin of symptoms in these patients, potentiating the mechanisms leading to physical deconditioning and further worsening of symptoms. This underlines the practical importance of studies focused on the possibility of modifying these control mechanisms. Recent evidence indicates that non-pharmacological interventions, such as general physical training, or, particularly, specific types of training of the respiratory pattern, may modify some of these reflex control mechanisms, including the chemoreflex response, and provide potential favorable effects in chronic heart failure.
| Original language | Italian |
|---|---|
| Pages (from-to) | 624-627 |
| Number of pages | 4 |
| Journal | Italian Heart Journal Supplement |
| Volume | 2 |
| Issue number | 6 |
| Publication status | Published - 2001 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Interazione tra controllo del respiro, funzione autonomica e pattern respiratorio nello scompenso cardiaco. Nuove possibilitá di intervento riabilitativo. / Porta, C.; Bernardi, L.
In: Italian Heart Journal Supplement, Vol. 2, No. 6, 2001, p. 624-627.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Interazione tra controllo del respiro, funzione autonomica e pattern respiratorio nello scompenso cardiaco. Nuove possibilitá di intervento riabilitativo
AU - Porta, C.
AU - Bernardi, L.
PY - 2001
Y1 - 2001
N2 - Some of the most invalidating symptoms in subjects with chronic heart failure, such as dyspnea and poor exercise tolerance, correlate poorly with indices of myocardial pump function, but are more related to alterations in autonomic nervous system, respiratory system, in addition to physical deconditioning. Increasing evidence suggests that in addition to pump function abnormalities, sympathetic and parasympathetic abnormalities, increased function of baro-, chemo- and ergoreflex control mechanisms play a pivotal role in the origin of symptoms in these patients, potentiating the mechanisms leading to physical deconditioning and further worsening of symptoms. This underlines the practical importance of studies focused on the possibility of modifying these control mechanisms. Recent evidence indicates that non-pharmacological interventions, such as general physical training, or, particularly, specific types of training of the respiratory pattern, may modify some of these reflex control mechanisms, including the chemoreflex response, and provide potential favorable effects in chronic heart failure.
AB - Some of the most invalidating symptoms in subjects with chronic heart failure, such as dyspnea and poor exercise tolerance, correlate poorly with indices of myocardial pump function, but are more related to alterations in autonomic nervous system, respiratory system, in addition to physical deconditioning. Increasing evidence suggests that in addition to pump function abnormalities, sympathetic and parasympathetic abnormalities, increased function of baro-, chemo- and ergoreflex control mechanisms play a pivotal role in the origin of symptoms in these patients, potentiating the mechanisms leading to physical deconditioning and further worsening of symptoms. This underlines the practical importance of studies focused on the possibility of modifying these control mechanisms. Recent evidence indicates that non-pharmacological interventions, such as general physical training, or, particularly, specific types of training of the respiratory pattern, may modify some of these reflex control mechanisms, including the chemoreflex response, and provide potential favorable effects in chronic heart failure.
KW - Autonomic nervous system
KW - Baroreflex
KW - Chemoreflex
KW - Ergoreflex
KW - Heart failure
KW - Ventilation
UR - http://www.scopus.com/inward/record.url?scp=0034923856&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034923856&partnerID=8YFLogxK
M3 - Articolo
C2 - 11460835
AN - SCOPUS:0034923856
VL - 2
SP - 624
EP - 627
JO - Italian Heart Journal Supplement
JF - Italian Heart Journal Supplement
SN - 1129-4728
IS - 6
ER -