Interaction of metals in nickel-sensitive patients

B. Santucci; C. Cannistraci; A. Cristaudo; M. Picardo

doi:10.1111/j.1600-0536.1993.tb03559.x

Interaction of metals in nickel-sensitive patients

B. Santucci, C. Cannistraci, A. Cristaudo, M. Picardo

Istituto S. Maria e S. Gallicano

Research output: Contribution to journal › Article

Abstract

Nickel (Ni) dermatitis is thought to involve the formation of complexes between Ni ions and suitable proteins. 4 groups of 30 subjects who gave positive patch test responses to NiSO₄ 2.9% aq. were each retested to 1 of 4 different solutions containing equimolar (0.1 M) amounts of NiSO₄ plus MgSO₄, NiSO₄ plus CuSO₄, NiSO₄ plus ZnSO₄, and NiSO₄ plus Li₂SO₄, respectively. The results, evaluated at 2 days by visual scoring only, demonstrated that the 4 metals exerted a different influence on the nickel reactions, perhaps interfering with one or more factors affecting the formation of Ni++ complexes.

Original language	English
Pages (from-to)	251-253
Number of pages	3
Journal	Contact Dermatitis
Volume	29
Issue number	5
DOIs	https://doi.org/10.1111/j.1600-0536.1993.tb03559.x
Publication status	Published - 1993

Fingerprint

Keywords

Allergic contact dermatitis
Chemical basis
Immunological basis
Ni++ complexes
Nickel sensitivity

ASJC Scopus subject areas

Dermatology
Toxicology
Immunology

Cite this

Santucci, B., Cannistraci, C., Cristaudo, A., & Picardo, M. (1993). Interaction of metals in nickel-sensitive patients. Contact Dermatitis, 29(5), 251-253. https://doi.org/10.1111/j.1600-0536.1993.tb03559.x

@article{f83a74d136004d3ca385e38557d87075,

title = "Interaction of metals in nickel-sensitive patients",

abstract = "Nickel (Ni) dermatitis is thought to involve the formation of complexes between Ni ions and suitable proteins. 4 groups of 30 subjects who gave positive patch test responses to NiSO4 2.9% aq. were each retested to 1 of 4 different solutions containing equimolar (0.1 M) amounts of NiSO4 plus MgSO4, NiSO4 plus CuSO4, NiSO4 plus ZnSO4, and NiSO4 plus Li2SO4, respectively. The results, evaluated at 2 days by visual scoring only, demonstrated that the 4 metals exerted a different influence on the nickel reactions, perhaps interfering with one or more factors affecting the formation of Ni++ complexes.",

keywords = "Allergic contact dermatitis, Chemical basis, Immunological basis, Ni++ complexes, Nickel sensitivity",

author = "B. Santucci and C. Cannistraci and A. Cristaudo and M. Picardo",

year = "1993",

doi = "10.1111/j.1600-0536.1993.tb03559.x",

language = "English",

volume = "29",

pages = "251--253",

journal = "Contact Dermatitis",

issn = "0105-1873",

publisher = "Wiley-Blackwell",

number = "5",

}

TY - JOUR

T1 - Interaction of metals in nickel-sensitive patients

AU - Santucci, B.

AU - Cannistraci, C.

AU - Cristaudo, A.

AU - Picardo, M.

PY - 1993

Y1 - 1993

N2 - Nickel (Ni) dermatitis is thought to involve the formation of complexes between Ni ions and suitable proteins. 4 groups of 30 subjects who gave positive patch test responses to NiSO4 2.9% aq. were each retested to 1 of 4 different solutions containing equimolar (0.1 M) amounts of NiSO4 plus MgSO4, NiSO4 plus CuSO4, NiSO4 plus ZnSO4, and NiSO4 plus Li2SO4, respectively. The results, evaluated at 2 days by visual scoring only, demonstrated that the 4 metals exerted a different influence on the nickel reactions, perhaps interfering with one or more factors affecting the formation of Ni++ complexes.

AB - Nickel (Ni) dermatitis is thought to involve the formation of complexes between Ni ions and suitable proteins. 4 groups of 30 subjects who gave positive patch test responses to NiSO4 2.9% aq. were each retested to 1 of 4 different solutions containing equimolar (0.1 M) amounts of NiSO4 plus MgSO4, NiSO4 plus CuSO4, NiSO4 plus ZnSO4, and NiSO4 plus Li2SO4, respectively. The results, evaluated at 2 days by visual scoring only, demonstrated that the 4 metals exerted a different influence on the nickel reactions, perhaps interfering with one or more factors affecting the formation of Ni++ complexes.

KW - Allergic contact dermatitis

KW - Chemical basis

KW - Immunological basis

KW - Ni++ complexes

KW - Nickel sensitivity

UR - http://www.scopus.com/inward/record.url?scp=0027421044&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027421044&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0536.1993.tb03559.x

DO - 10.1111/j.1600-0536.1993.tb03559.x

M3 - Article

C2 - 8112064

AN - SCOPUS:0027421044

VL - 29

SP - 251

EP - 253

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 5

ER -

Access to Document

10.1111/j.1600-0536.1993.tb03559.x