Interaction of metals in nickel-sensitive patients

B. Santucci; C. Cannistraci; A. Cristaudo; M. Picardo

doi:10.1111/j.1600-0536.1993.tb03559.x

Interaction of metals in nickel-sensitive patients

B. Santucci, C. Cannistraci, A. Cristaudo, M. Picardo

Istituto S. Maria e S. Gallicano

Research output: Contribution to journal › Article › peer-review

Abstract

Nickel (Ni) dermatitis is thought to involve the formation of complexes between Ni ions and suitable proteins. 4 groups of 30 subjects who gave positive patch test responses to NiSO₄ 2.9% aq. were each retested to 1 of 4 different solutions containing equimolar (0.1 M) amounts of NiSO₄ plus MgSO₄, NiSO₄ plus CuSO₄, NiSO₄ plus ZnSO₄, and NiSO₄ plus Li₂SO₄, respectively. The results, evaluated at 2 days by visual scoring only, demonstrated that the 4 metals exerted a different influence on the nickel reactions, perhaps interfering with one or more factors affecting the formation of Ni++ complexes.

Original language	English
Pages (from-to)	251-253
Number of pages	3
Journal	Contact Dermatitis
Volume	29
Issue number	5
DOIs	https://doi.org/10.1111/j.1600-0536.1993.tb03559.x
Publication status	Published - 1993

Keywords

Allergic contact dermatitis
Chemical basis
Immunological basis
Ni++ complexes
Nickel sensitivity

ASJC Scopus subject areas

Dermatology
Toxicology
Immunology

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AU - Santucci, B.

AU - Cannistraci, C.

AU - Cristaudo, A.

AU - Picardo, M.

PY - 1993

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N2 - Nickel (Ni) dermatitis is thought to involve the formation of complexes between Ni ions and suitable proteins. 4 groups of 30 subjects who gave positive patch test responses to NiSO4 2.9% aq. were each retested to 1 of 4 different solutions containing equimolar (0.1 M) amounts of NiSO4 plus MgSO4, NiSO4 plus CuSO4, NiSO4 plus ZnSO4, and NiSO4 plus Li2SO4, respectively. The results, evaluated at 2 days by visual scoring only, demonstrated that the 4 metals exerted a different influence on the nickel reactions, perhaps interfering with one or more factors affecting the formation of Ni++ complexes.

AB - Nickel (Ni) dermatitis is thought to involve the formation of complexes between Ni ions and suitable proteins. 4 groups of 30 subjects who gave positive patch test responses to NiSO4 2.9% aq. were each retested to 1 of 4 different solutions containing equimolar (0.1 M) amounts of NiSO4 plus MgSO4, NiSO4 plus CuSO4, NiSO4 plus ZnSO4, and NiSO4 plus Li2SO4, respectively. The results, evaluated at 2 days by visual scoring only, demonstrated that the 4 metals exerted a different influence on the nickel reactions, perhaps interfering with one or more factors affecting the formation of Ni++ complexes.

KW - Allergic contact dermatitis

KW - Chemical basis

KW - Immunological basis

KW - Ni++ complexes

KW - Nickel sensitivity

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Interaction of metals in nickel-sensitive patients

Abstract

Keywords

ASJC Scopus subject areas

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