Abstract
The intragastric of intraperitoneal administration of metergoline (2.5-10 mg/kg) stimulates dopamine (DA) synthesis in the rat and mouse brain. In vitro, metergoline blocks DA-sensitive adenylate cyclase and displaces H3-haloperidol from specific binding sites in striatal homogenates.
| Original language | English |
|---|---|
| Pages (from-to) | 2383-2391 |
| Number of pages | 9 |
| Journal | Life Sciences |
| Volume | 23 |
| Issue number | 24 |
| DOIs | |
| Publication status | Published - Dec 11 1978 |
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ASJC Scopus subject areas
- Pharmacology
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Interaction of metergoline with striatal dopamine system. / Spano, P. F.; Biggio, G.; Casu, M.; Gessa, G. L.; Bareggi, S. R.; Govoni, S.; Trabucchi, M.
In: Life Sciences, Vol. 23, No. 24, 11.12.1978, p. 2383-2391.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Interaction of metergoline with striatal dopamine system
AU - Spano, P. F.
AU - Biggio, G.
AU - Casu, M.
AU - Gessa, G. L.
AU - Bareggi, S. R.
AU - Govoni, S.
AU - Trabucchi, M.
PY - 1978/12/11
Y1 - 1978/12/11
N2 - The intragastric of intraperitoneal administration of metergoline (2.5-10 mg/kg) stimulates dopamine (DA) synthesis in the rat and mouse brain. In vitro, metergoline blocks DA-sensitive adenylate cyclase and displaces H3-haloperidol from specific binding sites in striatal homogenates.
AB - The intragastric of intraperitoneal administration of metergoline (2.5-10 mg/kg) stimulates dopamine (DA) synthesis in the rat and mouse brain. In vitro, metergoline blocks DA-sensitive adenylate cyclase and displaces H3-haloperidol from specific binding sites in striatal homogenates.
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UR - http://www.scopus.com/inward/citedby.url?scp=0018266308&partnerID=8YFLogxK
U2 - 10.1016/0024-3205(78)90296-5
DO - 10.1016/0024-3205(78)90296-5
M3 - Article
C2 - 745518
AN - SCOPUS:0018266308
VL - 23
SP - 2383
EP - 2391
JO - Life Sciences
JF - Life Sciences
SN - 0024-3205
IS - 24
ER -