TY - JOUR
T1 - Interaction of ultraviolet light with the cornea
T2 - Clinical implications for corneal crosslinking
AU - Lombardo, Marco
AU - Pucci, Giuseppe
AU - Barberi, Riccardo
AU - Lombardo, Giuseppe
PY - 2015/2/1
Y1 - 2015/2/1
N2 - Understanding ultraviolet (UV) interaction with the human corneal tissue is of interest among corneal specialists given the widespread application of corneal crosslinking. This article reviews the current knowledge of light interaction with the cornea in the UV wavelength range. It also uses a novel experimental study to illustrate the role of 2 important corneal properties that have not yet been clarified: the epithelial contribution to overall UVA corneal absorbance and the regional anisotropy of UVA light transmittance. Finally, it presents the most recent insights into how different methods of UVA light irradiation and corneal soaking with riboflavin influence the outcome of corneal crosslinking. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.
AB - Understanding ultraviolet (UV) interaction with the human corneal tissue is of interest among corneal specialists given the widespread application of corneal crosslinking. This article reviews the current knowledge of light interaction with the cornea in the UV wavelength range. It also uses a novel experimental study to illustrate the role of 2 important corneal properties that have not yet been clarified: the epithelial contribution to overall UVA corneal absorbance and the regional anisotropy of UVA light transmittance. Finally, it presents the most recent insights into how different methods of UVA light irradiation and corneal soaking with riboflavin influence the outcome of corneal crosslinking. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.
UR - http://www.scopus.com/inward/record.url?scp=84923124739&partnerID=8YFLogxK
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U2 - 10.1016/j.jcrs.2014.12.013
DO - 10.1016/j.jcrs.2014.12.013
M3 - Article
C2 - 25542349
AN - SCOPUS:84923124739
VL - 41
SP - 446
EP - 449
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
SN - 0886-3350
IS - 2
ER -