Interferon beta-related nephropathy and interstitial lung disease: A new association and a long-term warning

Marco Capobianco, Giorgina Piccoli, Federica Neve Vigotti, Paola Scapoli, Maria Chiara Deagostini, Carlo Albera, Dario Roccatello, Bertolotto Bertolotto

Research output: Contribution to journalArticle

Abstract

We report on a so-far never described association between glomerulonephritis and sarcoid-like lung disease after longterm interferon beta (IFNb) treatment for relapsing-remitting multiple sclerosis. The interest in this case resides in the documented remission after IFNb discontinuation. The history of IFNb-related adverse events is probably not yet completely written. The rapid reversal of the pathological signs in our patient underlines the importance of careful clinical and laboratory surveillance, including kidney functional parameters, for an early diagnosis of IFNb-related diseases.

Original languageEnglish
Pages (from-to)889-891
Number of pages3
JournalMultiple Sclerosis Journal
Volume20
Issue number7
DOIs
Publication statusPublished - 2014

Keywords

  • Adverse event
  • Disease-modifying therapies
  • Nephritis
  • Sarcoidosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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    Capobianco, M., Piccoli, G., Vigotti, F. N., Scapoli, P., Deagostini, M. C., Albera, C., Roccatello, D., & Bertolotto, B. (2014). Interferon beta-related nephropathy and interstitial lung disease: A new association and a long-term warning. Multiple Sclerosis Journal, 20(7), 889-891. https://doi.org/10.1177/1352458513519839