Interhemispheric integration of simple visuomotor responses in patients with partial callosal defects

G. Tassinari, S. Aglioti, R. Pallini, G. Berlucchi, G. F. Rossi

Research output: Contribution to journalArticle

Abstract

Because of the organization of visual and motor pathways, simple manual responses to a light stimulus in the right or left visual hemifields are performed faster with uncrossed hand-field combinations than with crossed hand-field combinations. Uncrossed responses can be integrated within a single hemisphere, whereas crossed responses require a time-consuming interhemispheric transfer via the corpus callosum which is reflected in the difference between crossed and uncrossed reaction times. We investigated crossed-uncrossed differences (CUDs) in speed of simple visuomotor responses to lateralized flashes in seven subjects with an anterior section of the corpus callosum sparing the splenium and in one subject with an agenetic absence of the splenium due to a cerebrovascular malformation. There was no evidence of an abnormal prolongation of the CUDs in any of these subjects, in sharp contrast with the very long CUDs exhibited by an epileptic subject with a complete callosal section and two subjects with total callosal agenesis tested in the same experimental situation [1]. The normality of the CUDs in the subjects with partial callosal defects was not due to a postoperatory reorganization of interhemispheric communication, since there was no indication of an increased CUD in a patient tested as early as 5 days after the anterior callosotomy. These results are compatible with the assumption that both anterior and posterior callosal routes may subserve the integration of speeded manual responses to a visual stimulus directed to the hemisphere ipsilateral to the responding hand.

Original languageEnglish
Pages (from-to)141-149
Number of pages9
JournalBehavioural Brain Research
Volume64
Issue number1-2
DOIs
Publication statusPublished - Oct 20 1994

Fingerprint

Corpus Callosum
Hand
Agenesis of Corpus Callosum
Efferent Pathways
Visual Pathways
Communication
Light

Keywords

  • Callosal agenesis
  • Callosotomy in man
  • Interhemispheric communication
  • Reaction time
  • Visuomotor integration

ASJC Scopus subject areas

  • Behavioral Neuroscience

Cite this

Interhemispheric integration of simple visuomotor responses in patients with partial callosal defects. / Tassinari, G.; Aglioti, S.; Pallini, R.; Berlucchi, G.; Rossi, G. F.

In: Behavioural Brain Research, Vol. 64, No. 1-2, 20.10.1994, p. 141-149.

Research output: Contribution to journalArticle

Tassinari, G. ; Aglioti, S. ; Pallini, R. ; Berlucchi, G. ; Rossi, G. F. / Interhemispheric integration of simple visuomotor responses in patients with partial callosal defects. In: Behavioural Brain Research. 1994 ; Vol. 64, No. 1-2. pp. 141-149.
@article{f02a37708622439888a137b69847bf93,
title = "Interhemispheric integration of simple visuomotor responses in patients with partial callosal defects",
abstract = "Because of the organization of visual and motor pathways, simple manual responses to a light stimulus in the right or left visual hemifields are performed faster with uncrossed hand-field combinations than with crossed hand-field combinations. Uncrossed responses can be integrated within a single hemisphere, whereas crossed responses require a time-consuming interhemispheric transfer via the corpus callosum which is reflected in the difference between crossed and uncrossed reaction times. We investigated crossed-uncrossed differences (CUDs) in speed of simple visuomotor responses to lateralized flashes in seven subjects with an anterior section of the corpus callosum sparing the splenium and in one subject with an agenetic absence of the splenium due to a cerebrovascular malformation. There was no evidence of an abnormal prolongation of the CUDs in any of these subjects, in sharp contrast with the very long CUDs exhibited by an epileptic subject with a complete callosal section and two subjects with total callosal agenesis tested in the same experimental situation [1]. The normality of the CUDs in the subjects with partial callosal defects was not due to a postoperatory reorganization of interhemispheric communication, since there was no indication of an increased CUD in a patient tested as early as 5 days after the anterior callosotomy. These results are compatible with the assumption that both anterior and posterior callosal routes may subserve the integration of speeded manual responses to a visual stimulus directed to the hemisphere ipsilateral to the responding hand.",
keywords = "Callosal agenesis, Callosotomy in man, Interhemispheric communication, Reaction time, Visuomotor integration",
author = "G. Tassinari and S. Aglioti and R. Pallini and G. Berlucchi and Rossi, {G. F.}",
year = "1994",
month = "10",
day = "20",
doi = "10.1016/0166-4328(94)90126-0",
language = "English",
volume = "64",
pages = "141--149",
journal = "Behavioural Brain Research",
issn = "0166-4328",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Interhemispheric integration of simple visuomotor responses in patients with partial callosal defects

AU - Tassinari, G.

AU - Aglioti, S.

AU - Pallini, R.

AU - Berlucchi, G.

AU - Rossi, G. F.

PY - 1994/10/20

Y1 - 1994/10/20

N2 - Because of the organization of visual and motor pathways, simple manual responses to a light stimulus in the right or left visual hemifields are performed faster with uncrossed hand-field combinations than with crossed hand-field combinations. Uncrossed responses can be integrated within a single hemisphere, whereas crossed responses require a time-consuming interhemispheric transfer via the corpus callosum which is reflected in the difference between crossed and uncrossed reaction times. We investigated crossed-uncrossed differences (CUDs) in speed of simple visuomotor responses to lateralized flashes in seven subjects with an anterior section of the corpus callosum sparing the splenium and in one subject with an agenetic absence of the splenium due to a cerebrovascular malformation. There was no evidence of an abnormal prolongation of the CUDs in any of these subjects, in sharp contrast with the very long CUDs exhibited by an epileptic subject with a complete callosal section and two subjects with total callosal agenesis tested in the same experimental situation [1]. The normality of the CUDs in the subjects with partial callosal defects was not due to a postoperatory reorganization of interhemispheric communication, since there was no indication of an increased CUD in a patient tested as early as 5 days after the anterior callosotomy. These results are compatible with the assumption that both anterior and posterior callosal routes may subserve the integration of speeded manual responses to a visual stimulus directed to the hemisphere ipsilateral to the responding hand.

AB - Because of the organization of visual and motor pathways, simple manual responses to a light stimulus in the right or left visual hemifields are performed faster with uncrossed hand-field combinations than with crossed hand-field combinations. Uncrossed responses can be integrated within a single hemisphere, whereas crossed responses require a time-consuming interhemispheric transfer via the corpus callosum which is reflected in the difference between crossed and uncrossed reaction times. We investigated crossed-uncrossed differences (CUDs) in speed of simple visuomotor responses to lateralized flashes in seven subjects with an anterior section of the corpus callosum sparing the splenium and in one subject with an agenetic absence of the splenium due to a cerebrovascular malformation. There was no evidence of an abnormal prolongation of the CUDs in any of these subjects, in sharp contrast with the very long CUDs exhibited by an epileptic subject with a complete callosal section and two subjects with total callosal agenesis tested in the same experimental situation [1]. The normality of the CUDs in the subjects with partial callosal defects was not due to a postoperatory reorganization of interhemispheric communication, since there was no indication of an increased CUD in a patient tested as early as 5 days after the anterior callosotomy. These results are compatible with the assumption that both anterior and posterior callosal routes may subserve the integration of speeded manual responses to a visual stimulus directed to the hemisphere ipsilateral to the responding hand.

KW - Callosal agenesis

KW - Callosotomy in man

KW - Interhemispheric communication

KW - Reaction time

KW - Visuomotor integration

UR - http://www.scopus.com/inward/record.url?scp=0028032749&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028032749&partnerID=8YFLogxK

U2 - 10.1016/0166-4328(94)90126-0

DO - 10.1016/0166-4328(94)90126-0

M3 - Article

C2 - 7840880

AN - SCOPUS:0028032749

VL - 64

SP - 141

EP - 149

JO - Behavioural Brain Research

JF - Behavioural Brain Research

SN - 0166-4328

IS - 1-2

ER -